colestipol


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Related to colestipol: colestipol hydrochloride

colestipol

(kəˈlɛstɪˌpɒl)
n
(Pharmacology) a drug that reduces the concentration of cholesterol in the blood: used, together with dietary restriction of cholesterol, to treat selected patients with hypercholesterolaemia and so prevent atherosclerosis
Translations

colestipol

n colestipol m
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References in periodicals archive ?
The bile acid resins segment included resins such as Cholestyramine, Colestipol, Colesevelam, and Cholybar.
Diclofenac bioavailability can be reduced by a variety of agents including colestipol, cholestyramine (Al-Balla et al.
Based on the differential diagnosis, he was initially managed with soluble fiber, colestipol, and loperamide, which achieved constipation.
In the Familial Atherosclerosis Treatment Study (FATS) (29, 30), 126 men with known CHD were randomized to receive conventional therapy or lovastatin plus colestipol or niacin (4 g/day).
33) Patients were randomized to one of three groups: lovastatin 20 mg twice daily plus colestipol 30 g/day, IR niacin 1 g four times daily plus colestipol 30 g/day, or placebo plus colestipol 30/ gm daily.
Bile acid sequestrants: Colestyramine and colestipol bind to bile acids in the small intestine and prevent their reabsorption across the gut wall.
Drugs that influence thyroid function (29) Drugs that decrease TSH secretion Dopamine Glucocorticoids Ocreotide Drugs that decrease thyroid hormone secretion Lithium Iodide Amiodarone Drugs that increase thyroid hormone secretion Iodide Amiodarone Drugs that decrease T4 absorption Colestipol Cholestyramine Aluminium hydroxide Ferrous sulphate Drugs that affect thyroid hormone transport Oestrogen Tamoxifen Heroin Methadone Androgens Glucocorticoids Salicylates Anabolic steroids Drugs that increase hepatic metabolism of T4 and T3 Phenobarbitol Rifampicin Phenytoin Carbamazepine Decreased T4 5'-deiodinase activity Amiodarone Glucocorticoids Propylthoiuracil Beta-adrenergic antagonists Fig.
Note that cholestyramine and colestipol also deplete cholesterol.
Cholestyramine and colestipol are usually prepared as powders mixed with water or orange juice.
In addition, at least 3 trials with bile acid sequestration have demonstrated reduction in cardiovascular disease events, the POSCH (Partial Ileal Bypass Surgery), Lipid Research Clinics-Coronary Primary Prevention Trial, and Colestipol Trial.
Three BAS are currently used for treating hypercholesterolemia in the United States: the conventional sequestrants, cholestyramine and colestipol, and the specifically engineered BAS, colesevelam hydrochloride (HCl).
The Familial Atherosclerosis Treatment Study (FATS) found niacin, lovastatin, and colestipol significantly reduced atherosclerosis progression, cardiovascular events, and deaths, compared with usual care at 10 years' follow-up (Am.