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 (kŏl′ĭ-sĭn, kō′lĭ-)
Any of various antibacterial proteins produced by certain strains of E. coli that inhibit or kill closely related species or strains of bacteria.

[New Latin colī, specific epithet of Escherichia colī; see E. coli + -(i)c + -in.]


(ˈkɒlɪsɪn) or


a bacteriocidal protein
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References in periodicals archive ?
Klebsiella 370 Sulfonamide, Trimethoprim, Quinolone, Acriflavin, Glyoxalase, Bleomycin Tetracycline, Gentamicin, Tobramycin, Amikacin, Streptomycin, Colicin, Tunicamycin, Chloramphenicol,Fosfomycin, Florfenicol, Erythromycin, kanamycin, Neomycin, Apramycin, Trimethoprim, Rifampin and Spectinomycin Acinetobacter 212 Sulfonamide, Trimethoprim, Aminoglycoside,Gentamicin, Bleomycin, Carbapenem, Amikacin, Kanamycin and Neomycin.
These include K antigen, Somatic O antigen, Pili/Fimbriae (Type-1 fimbriae, P fimbriae, S fimbriae, PAP), Afimbrial adhesins, Haemagglutination of erythrocytes, Haemolysin, Resistance to the bactericidal activity of Serum, Cell Surface Hydrophobicity, expression of Siderophore Aerobactin, production of Colicin V and Cytotoxic Necrotizing Factor.
The cba gene (encoding for a bacteriocin, 2 isolates), the cma gene (also encoding for a colicin, 2 isolates), the cdtB gene (encoding for a cytolethal distending toxin, 3 isolates), and the cnf1 gene (encoding for a cytotoxic necrotizing factor type 1, 3 isolates) were amplified in some isolates.
Sequence homology analysis has revealed that Usp shares homology with nuclease-type bacteriocins such as colicin E9 and pyocin AP41.
coli bacteria, called Colicin N, which kills competing bacteria in a very efficient way.