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colony stimulating factor

   Also found in: Medical, Acronyms, Wikipedia 0.03 sec.
colony stimulating factor
n.
A hormone produced in the cells lining the blood vessels that stimulates the bone marrow to synthesize white blood cells.

colony stimulating factor
Any of various glycoproteins that act to promote the production and differentiation of specific blood cell types. Colony stimulating factors circulate in the blood, acting as hormones, and are also secreted locally. An example is erythropoietin, which is produced in the kidney and regulates the formation of red blood cells from progenitor cells in the bone marrow.


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The drug, a bioengineered form of a natural protein called granulocyte colony stimulating factor, is already used by people who've donated marrow to others and by cancer patients.
Phase I trial of m-BACOD and granulocyte macrophage colony stimulating factor in HIV-associated non-Hodgkin's lymphoma.
One of the colony stimulating factor drugs is Neu Pogen, which is much used to stimulate white blood cells to come back faster after higher doses of chemotherapy.
 
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