combination therapy


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combination therapy

n.
The simultaneous use of multiple drugs or other agents as part of a treatment regimen against a specific disease to improve effectiveness, prevent the development of drug resistance, and minimize side effects.
References in periodicals archive ?
5%) on 1 or 2 oral agents, beginning combination therapy is more effective than adding another oral agent (SOR: B, based on subpopulation analysis in RCTs).
Results of phase III clinical trials for the combination therapy of PEGASYS and rivabirin were presented at the 41st Annual Conference of the Japan Society of Hepatology held in Osaka in June.
In the study, 198 patients on combination therapy had significantly higher cognitive performance on the Severe Impairment Battery than did 197 patients on donepezil plus placebo at the end of the 24-week trial, which was funded by Forest Laboratories Inc.
5%) women who received combination therapy transmitted HIV to their infants, compared with 20 of 477 (4.
The combination therapy, including drugs meant to block the virus from making copies of itself, had raised great hopes because in many patients it reduced the human immunodeficiency virus in the bloodstream to levels that could not be detected by standard tests.
According to the partnership, the closed triple combination therapy comprises three medicines: fluticasone furoate, an inhaled corticosteroid (ICS), umeclidinium, a long-acting muscarinic antagonist (LAMA) and vilanterol, a long-acting beta2-adrenergic agonist (LABA), delivered once-daily in GSK's Ellipta dry powder inhaler.
Neutel acknowledged that the results from many prior studies had already proved the added efficacy and safety of combination therapy, but he stressed the importance of adding to this evidence base.
While the amount of HIV in the bloodstream can drop to undetectable levels with combination therapy, the effect on the quantity of virus in semen and vaginal secretions has remained unknown.
He then told of another doctor who after a year took his patient off combination therapy that did not include a protease inhibitor.
The Company's scientists demonstrated that mice previously treated with the IgNP/MCT-465 combination therapy which demonstrated tumor remission, remained immune to the development of new cancers even when challenged with a new tumorigenic dose of homologous tumor cells.
Pharmaceutical company GlaxoSmithKline plc (LSE:GSK)(NYSE:GSK) said on Monday that it has filed a regulatory submission with the US Food and Drug Administration for the once-daily, closed triple combination therapy fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI 100/62.