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complement fixation

   Also found in: Medical, Legal, Financial, Acronyms, Encyclopedia, Wikipedia, Hutchinson 0.02 sec.
complement fixation
n.
The binding of active serum complement to an antigen-antibody pair. It is the basis for various diagnostic tests to detect the presence of a specific antigen or antibody.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.complement fixation - an immune response in which an antigen-antibody combination inactivates a complement (so it is unavailable to participate in a second antigen-antibody combination)
immune reaction, immune response, immunologic response - a bodily defense reaction that recognizes an invading substance (an antigen: such as a virus or fungus or bacteria or transplanted organ) and produces antibodies specific against that antigen


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capsulatum was positive for H and M bands, but a specimen was not submitted to the Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA, for complement fixation testing.
Histoplasmosis cluster, golf course, Canada by Probert, Steven / Emerging Infectious Diseases
A complement fixation assay has been developed for detection of EYAV (6).
Coltiviruses and seadornaviruses in North America, Europe, and Asia by de Lamballerie, Xavier / Emerging Infectious Diseases
The virus was identified by complement fixation test and confirmed by reverse transcription--polymerase chain reaction.
Oropouche virus isolation, Southeast Brazil by Vasconcelos, Pedro Fernando da Costa / Emerging Infectious Diseases
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