conformation

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con·for·ma·tion

 (kŏn′fər-mā′shən)
n.
1. The act of conforming or the state of being conformed.
2. The structure or outline of an item or entity, determined by the arrangement of its parts.
3. A symmetrical arrangement of the parts of a thing.
4. One of the spatial arrangements of atoms in a molecule that can come about through free rotation of the atoms about a chemical bond.

con′for·ma′tion·al adj.
con′for·ma′tion·al·ly adv.

conformation

(ˌkɒnfɔːˈmeɪʃən)
n
1. the general shape or outline of an object; configuration
2. the arrangement of the parts of an object
3. the act or state of conforming
4. (Chemistry) chem
a. another name for configuration3a
b. one of the configurations of a molecule that can easily change its shape and can consequently exist in equilibrium with molecules of different configuration
ˌconforˈmational adj

con•for•ma•tion

(ˌkɒn fɔrˈmeɪ ʃən)

n.
1. structure; form, as of a physical entity.
2. symmetrical arrangement of parts.
3. the act or process of conforming; adaptation.
4. the state of being conformed.
5. an atomic spatial arrangement that results from rotation of carbon atoms about single bonds within an organic molecule (contrasted with configuration).
[1505–15; < Latin]
con`for•ma′tion•al, adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.conformation - a symmetrical arrangement of the parts of a thingconformation - a symmetrical arrangement of the parts of a thing
equipoise, counterbalance, equilibrium, balance - equality of distribution
2.conformation - any spatial attributes (especially as defined by outline)conformation - any spatial attributes (especially as defined by outline); "he could barely make out their shapes"
keenness, sharpness - thinness of edge or fineness of point
bluntness, dullness - without sharpness or clearness of edge or point; "the dullness of the pencil made his writing illegible"
spatial property, spatiality - any property relating to or occupying space
topography - the configuration of a surface and the relations among its man-made and natural features
lobularity - the property of having lobules
concaveness, concavity - the property possessed by a concave shape
convexity, convexness - the property possessed by a convex shape
angularity - the property possessed by a shape that has angles
narrowing - an instance of becoming narrow
curvature, curve - the property possessed by the curving of a line or surface
roundness - the property possessed by a line or surface that is curved and not angular
straightness - freedom from crooks or curves or bends or angles
crookedness - having or distinguished by crooks or curves or bends or angles
stratification - a layered configuration
3.conformation - acting according to certain accepted standardsconformation - acting according to certain accepted standards; "their financial statements are in conformity with generally accepted accounting practices"
cooperation - joint operation or action; "their cooperation with us was essential for the success of our mission"
formality - compliance with formal rules; "courtroom formality"
line - acting in conformity; "in line with"; "he got out of line"; "toe the line"
honoring, observance - conformity with law or custom or practice etc.
keeping - conformity or harmony; "his behavior was not in keeping with the occasion"

conformation

noun shape, build, form, structure, arrangement, outline, framework, anatomy, configuration Poor conformation means a horse is more susceptible to injury.

conformation

noun
1. The act of making suitable to an end or the condition of being made suitable to an end:
Translations
alakzatalkalmazkodásstruktúraszerkezet

conformation

[ˌkɒnfəˈmeɪʃən] Nconformación f, estructura f
References in periodicals archive ?
GPCRs are flexible signaling switches located in the cell membrane and pass outside signals into the cell through conformational changes.
Upon addition of simple chemical additives forming competitive intermolecular hydrogen bonds with the foldamer, The directionality of these networks could be modified, Transforming a conformational mixture to a well-defined unidirectional network.
Crenezumab is shown to bind to a unique sequential, conformational epitope that only exists in the aggregated form of Abeta.
Studies of conformational changes in proteins as well as unprecedented utility for applications such as point-of-care biosensors and food/environmental safety research are now possible thanks to the BI-4500 system's novel analysis modules.
com)-- Terry Hebert, Professor of Pharmacology and Therapeuticsat at McGill University, will give a presentation on, "Assessing Bias and Allostery in GPCRs using Conformational Biosensors" at GTCbio's 4th GPCR in Drug Discovery Conference to be held on September 14-15, 2016 in Boston, MA.
Crelux provides a number of customised services to support hit-finding, conformational analysis and lead optimisation, including protein production, biophysical assays, fragment screening, and X-ray crystallography.
3% of examined textbooks (total of twelve) failed to simultaneously discuss the basic elements of the concept, (1) conformational change and (2) chemical interaction between the substrate and catalytic amino acids.
To obtain converged affinity results it was necessary to apply conformational, axial, and orientational restraints to the protein internal coordinates.
In eight chapters, they discuss its history and basic pharmacological principles, the role of the cell background in biased signaling, the application of signaling bias to new therapeutic drug therapy for seven transmembrane (G protein-coupled) receptors, biased signaling and conformational dynamics in nuclear hormone receptors, biasing receptor tyrosine kinase signaling pathways, conformational mechanisms of signaling bias of ion channels, protein conformational dynamics and signaling in evolution and pathophysiology, and the possibilities of biased signaling in the development of improved therapeutics.
The researchers documented that an allosteric trigger by a fragment of the cell wall at a distance of 60 Angstroms (6 nanometers) activates a set of conformational changes that culminates in the opening of the active site from a closed conformation, enabling catalysis for the physiological role of the enzyme.
But temperature isn't the only way to achieve this conformational change.