constant region


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constant region

n.
The portion of an immunoglobulin molecule's heavy and light chains that determines the class or subclass of the immunoglobulin and that is almost identical in amino acid sequence in all molecules of a particular class or subclass.
References in periodicals archive ?
It can be seen that the FEM curve can be divided into two regions: the constant region (below the straight line) over the whole hinge, which is almost in accordance with the basic theoretical stress curve, and the variable region (above the straight line), which follows the normal distribution curve.
The best example is the CTLA4-Ig fusion protein, containing the extracellular domain of CTLA-4 and the constant region of human IgG antibody.
It was reported on Friday that the contract has been signed to explore the mechanism of action of constant region variants of the HuMab 5B1 in the role of tumour clearance.
The identified proteins were conglutinin precursor, bovine fibrinogen, IgG1 heavy chain constant region, hemoglobin, complement component 3 and IgG2a heavy chain constant region.
The platform is planned to facilitate rapid discovery and development of bispecific antibodies by engineering additional binding sites into the constant region of an antibody.
Thus, the strategy in the constant region could be determined.
At the frequency points in which the complex waves disappear, the dispersion curves bifurcate in the attenuation constant region of the propagation constant at a certain frequency, [OMEGA] = 1.
Region identifier (rif): An identifier indicates whether its corresponding region is a constant region or an interval region.
L chains of a single chain monoclonal antibody to CD19, Fc represents at least part of a constant region of an IgG.
gonorrhoeae were negative, and notable levels of antibodies against a constant region of the major outer membrane protein of C.
A constant region of shear strength was determined where compressive field action no longer influenced the shear strength results.

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