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 (kŏn′stĭ-to͞o′tĭv, -tyo͞o′-)
1. Making a thing what it is; essential.
2. Having power to institute, establish, or enact.
3. Of or relating to the synthesis of a protein or an enzyme at a constant rate regardless of physiological demand or the concentration of a substrate.

con′sti·tu′tive·ly adv.
References in periodicals archive ?
Furthermore, some genes avoid or escape XCI altogether, either constitutively or in a tissue or stage-specific fashion, but the molecular basis for this is unclear.
sakazakii appears to constitutively express high levels of a-glucosidase.
Indoleamine 2,3-dioxygenase (IDO1) and Tryptophan 2,3-dioxygenase (TDO2), key enzymes in tryptophan catabolism, are constitutively expressed in many cancers, which often express one of the two enzymes.
com)-- The TSB grant will fund a collaborative project to develop synthetic promoters that constitutively drive high levels of gene expression in mammalian cell lines.
So, whilst writing that script for erection-promoting tablet, the Physician should also consider the possibility of hypovitaminosis D, particularly if the following risk factors are present: constitutively darker skin type, conscious or unconscious sun-avoidance behaviour, including culturally or behaviourally-determined forms of clothing, routine use of SPF sunblock in everyday life, shift work, obesity, medication with immunosuppressants or anticonvulsants, or bowel disease predisposing to fat soluble vitamin malabsorbtion.
Instead, an utterer of the Liar is performing a false act because his performance fails to approach the goal at which acts of assertion are constitutively aimed.
Further, we show that activation of p38 MAPK by expression of constitutively active MAP kinase kinase 6 (MKK6Glu) greatly enhances nuclear translocation of Xbp1s, reduces endoplasmic reticulum stress and establishes euglycemia in severely obese and diabetic mice.
b) principles constitutively a priori of geometry and mechanics (similar to Kuhnian paradigms and, as a consequence, not immutable but subject to deep changes during the periods of conceptual revolution);
Teffs constitutively expressed both [gamma]IFN and IL4--prototypical cytokines of Th1 and Th2 respectively; were able to proliferate and secrete higher quanitities of both cytokines in response to both antiCD3/antiCD28 and autologous tumour lysates.
1A]-adrenergic receptors (ARs) increases neurogenesis, learning, and memory in mice with constitutively active mutant (CAM) [[alpha].
3]-induced inhibition in myotube formation and muscle-specific protein expression was reversed by transfection with the constitutively active form of Akt.
continues, "contributes constitutively to general anthropology" but "not by providing an entirely new point of departure.