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cornification

   Also found in: Medical, Encyclopedia 0.01 sec.
cor·ni·fi·ca·tion  (kôrn-f-kshn)
n.
The conversion of squamous epithelial cells into a keratinized horny material, such as hair, nails, or feathers.
[Latin corn, horn; see ker-1 in Indo-European roots + -fication.]
cornification
organic change into a hornlike form.
See also: Bones
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This layer is constantly abraded by chemical and physical agents and renewed by a very slow process of cornification, which transforms keratinocytes into corneocytes.
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This means that hair is produced from the epidermis but its production is a process that forms a cornified cylinder, projected form the cutaneous surface and is very analogous to real epidermal cornification.
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Chapter 6 is about the effects of retinoids on the sebaceous gland, essentially on the treatment of acne with tretinoin, tazarotene, and adapalene topically, and isotretinoin orally, with detailed consideration of irritation and other side-effects, and chapter 8 deals with retinoid treatment of disorders of cornification such as ichthyosis.
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