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corticofugal

   Also found in: Medical 0.06 sec.
adj.1.same as corticoefferent; as, corticofugal discharges.
ThesaurusLegend:  Synonyms Related Words Antonyms
Adj.1.corticofugal - of a nerve fiber passing outward from the cerebral cortex; "corticofugal discharges"
efferent, motorial - of nerves and nerve impulses; conveying information away from the CNS; "efferent nerves and impulses"


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Lesions involving the internal capsule have the poorest outcome for motor abilities because of the condensed organization of corticofugal projections and the density of pyramidal fibers from the primary motor cortex in this subsector.
For instance, myelinization is not yet complete,[17] neurons within the brain have not completely differentiated,[18,19] there is an over-abundance of neurons in certain areas such as the spinal cord,[20] and some corticofugal projections (projections from the cerebral cortex to the brain stem and spinal cord) project to inappropriate targets (ie, locations at which connections are not found in the adult animal).
 
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