A San Diego, CA-based developer of a proprietary corticotropin
product candidate, Eton Pharmaceuticals, has raised $20M in Series A financing.
A team of researchers led by Mikito Takefuji from Nagoya University School of Medicine discovered that a signalling protein called corticotropin
releasing hormone receptor 2 (Crhr2) is expressed on the surface of heart muscle cells, or cardiomyocytes, and that Crhr2 levels increase in mice suffering from heart failure.
M2 EQUITYBITES-January 18, 2017-ANI names Karen Quinn PhD as VP, Corticotropin
M2 PHARMA-January 18, 2017-ANI names Karen Quinn PhD as VP, Corticotropin
The researchers collected patient demographics, hospital length of stay, hospital admission cost, use of various diagnostic studies (such as lumbar puncture, brain MRI, and EEG), and medications used for infantile spasms (including antiepileptic drugs, corticotropin
, and steroids).
NASDAQ: ANIP) has closed the acquisition of the NDAs for purified corticotropin
gel and corticotropin
-zinc hydroxide from US-based drugmaker Merck for USD 75m in cash and a percentage of future net sales, the company said.
is acquiring the New Drug Applications for purified corticotropin
gel and corticotropin
-zinc hydroxide from Merck & Co.
Activation of brain corticotropin
releasing factor (CRF) receptors mediates stress-related inhibition of upper GI and stimulation of lower GI motor function through interaction with different CRF receptor subtypes.
A hypothalamic hormone, corticotropin
-releasing hormone, controls the release of corticotropin
from the anterior pituitary gland.
Hypothalamic-pituitary-adrenal axis functioning and cerebrospinal fluid corticotropin
releasing hormone and corticotropin
levels in alcoholics after recent and long-term abstinence.
releasing factor (CRF), a neuropeptide, is known to be related to these physiological functions and neurological disorders.
The Phase 2 trial, which involved 150 patients experiencing a major depressive episode, found no benefit for patients treated with the experimental drug, a corticotropin
releasing factor (CRF1) receptor antagonist called GSK561679.