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corticotropin-releasing hormone

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia, Hutchinson 0.01 sec.
cor·ti·co·tro·pin-re·leas·ing hormone  (kôrt-k-trpn-r-lsng)
n. Abbr. CRH
A hormone produced by the hypothalamus that stimulates the anterior pituitary gland to release adrenocorticotropic hormone.


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One likely messenger is corticotropin-releasing hormone (CRH), ordinarily a stress hormone secreted by the brain but produced in pregnancy by the baby's placenta.
That finding suggests that the entire "fight-or-flight" stress-response system based on corticotropin-releasing hormone (CRH) dates back to a common ancestor of vertebrates and insects.
The PVN of the hypothalamus has a large number of corticotropin-releasing hormone neuronal cell bodies and receives rich noradrenergic innervation from the brainstem, through the ventral noradrenergic bundle (Petrusz and Merchenthaler 1992).
 
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