These are Tubular (well-differentiated or grade I), cribriform
(moderately differentiated or grade II) and solid pattern (poorly differentiated or grade III).
The main architectural patterns of HGPIN include micropapillary, tufting, flat, and cribriform
(Figure 1, A through D), but there are no known clinically relevant differences among these architectural patterns; their recognition is useful merely for diagnostic purposes.
It is well known that Neisseria meningitides can penetrate the cribriform
plate and reach the meninges causing meningitis.
As a result of numerous studies indicating the adverse prognosis of cribriform
glands, they have not been allowed in Gleason pattern 3 anymore.
Type 2 is characterised by a cribriform
arrangement of tumour cells.
The posterior ethmoid cells are then carefully opened, avoiding injury to the orbit laterally and the cribriform
Endoscopic examination of the cribriform
plate area was difficult owing to the distortion of the middle turbinate superiorly.
These cells are arranged into microcystic, cribriform
, tubular, papillary, follicular (thyroid like), or solid nests (Figure 1).
The dorsal nasal turbinate was the longest and extended from level of third transverse rugae of hard palate to level of cribriform
plate of ethmoid bone and it continued rostrally as straight fold.
Similar yellow gelatinous material obliterated the right ethmoturbinates rostral to the cribriform
This list is likely to grow with controversial newer additions such as cribriform
adenocarcinomas of the minor salivary glands (CAMSG), thanks to the rapid advancements of next generation sequencing and genomic and expression profiling methods, happening in the arena of molecular diagnostics.
Amebae are aspirated into the nasal cavity through swimming, splashing, or nasal irrigation, and after attaching to the nasal mucosa, migrate across the cribriform
plate to the brain via the olfactory nerves, causing extensive damage to the frontal lobes of the brain (1).