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(krôs′rĭ-zĭs′təns, krŏs′-)
Tolerance to a usually toxic substance as a result of exposure to a similarly acting substance: Some insects develop cross-resistance to insecticides.


1. immunologic resistance to the pathogenic effects of a microorganism due to previous exposure to another species or type having cross-reactive antigens.
2. (of an insect, bacterium, etc.) resistance to the effects of a pesticide, antibiotic, etc., due to previously acquired resistance to a similar substance.
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References in periodicals archive ?
These results were published in PLOS ONE under the title, Novel anti-cancer drug COTI-2 synergizes with therapeutic agents and does not induce resistance or exhibit cross-resistance in human cancer cell lines.
According to the antifungal resistance data of this study, cross-resistance between fluconazole and voriconazole was found among 18(8.
sup][23],[24] We found that one itraconazole-resistant isolate harbored the TR34/L98H mutation was cross-resistance to both voriconazole and posaconazole.
The fluoroquinolone strains seen in recurrent P aeruginosa showed high cross-resistance to other drugs.
Cross-resistance, stability, and fitness cost of resistance to imidacloprid in Musca domestica L.
Dr Bin Dayna explained that when microbes in the body over a period of time secure their 'own biological right to ensure their survival' they develop 'specific and cross-resistance capabilities'.
Hence, not all observed ET resistance can be attributed to use of this drug in clinical settings and to the role of cross-resistance with INH due to mutations in the inhA gene and others.
Results: P-glycoprotein- or BCRP overexpressing tumor cells did not reveal cross-resistance to reserpine.
Both health boards said the men " had previously taken another drug, abiraterone, and there were concerns about cross-resistance.
In contrast, owing to the structural and functional similarity between AMK and KAN, there is extensive cross-resistance between them.