The patient received a massive transfusion (16 units of red cell concentrate, 15 units of fresh frozen plasma and 2 units of platelets; cryoprecipitate
was not available) intraoperatively, and in addition, tranexamic acid, conjugated equine oestrogen (Premarin) and desmopressin were administered.
We're supporting patients with hemophilia by harvesting cryoprecipitate
(frozen blood product prepared from plasma) for them and allocating it for free.
NHS Blood and Transplant wishes to procure new rapid plasma freezers which will be required to freeze all appropriate apheresis and whole blood derived plasma components, along with cryoprecipitate
components, to the appropriate core temperatures in the time frames specified in the Guidelines for Blood Transfusion Services in the UK current edition and the Council of Europe guidelines
DIC is associated with a high mortality rate and may necessitate fresh-frozen plasma and/or cryoprecipitate
Solvent-detergent filtered (SD-F) fresh frozen plasma and cryoprecipitate
minipools prepared in a newly designed integral disposable processing bag system.
The patient was given cryoprecipitate
and a heparin infusion, and her fibrinogen transiently rose to 153 mg/dL.
Factor concentrates are increasingly preferred due to their lower infection risks over older alternatives such as FFP and cryoprecipitate
in critical care settings.
There has been an overall increase in the collection of blood products including packed cells (PC), fresh frozen plasma (FFP), cryoprecipitate
(CRYO), and single donor platelets (SDP).
Packed red blood cells may need to be issued, fresh frozen plasma and cryoprecipitate
need to be thawed, and platelets may also need to be issued.
When fibrinogen is needed, cryoprecipitate
is more efficient, since it contains 200-300 mg fibrinogen in each bag and does not lead to volume load.
In total, four units of cross-matched red blood cells, three bags of pooled platelets, seven units of cryoprecipitate
and 15 ml/kg of flesh frozen plasma were given to provide adequate haemostasis for chest closure.
The patient developed severe bleeding postoperatively despite receiving additional tranexamic acid, protamine, cryoprecipitate
, and infusion of plasma and platelets.