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guanosine
(redirected from cyclic guanosine monophosphate)

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
gua·no·sine  (gwän-sn, -sn)
n.
A nucleoside, C10H13N5O5, consisting of guanine and ribose.


guanosine [ˈgwɑːnəˌsiːn -ˌziːn]
n
(Life Sciences & Allied Applications / Biochemistry) Biochem a nucleoside consisting of guanine and ribose
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.guanosine - a nucleoside component of DNA; composed of guanine and deoxyribose
nucleoside - a glycoside formed by partial hydrolysis of a nucleic acid


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Along with increasing blood flow in arteries, Viagra interferes with phosphodiesterases (PDEs), enzymes that break down the messenger molecule called cyclic guanosine monophosphate (cGMP), which would otherwise "put the brakes on" heart muscle cell growth.
These drugs work mainly by blocking the enzyme PDE5, thus maintaining the level of cyclic guanosine monophosphate (GMP).
By blocking the PDE5 enzyme, levels of cyclic guanosine monophosphate (GMP) are maintained, thus increasing the level of nitric oxide during sexual stimulation.
 
 
 
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