cyclize


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Related to cyclize: Cyclizine

cyclize

(ˈsaɪklaɪz) or

cyclise

vb (tr)
to cause (a compound) to undergo cyclization
References in periodicals archive ?
Adding of compound 1 to ylidene malononitrile would yielded polyfunctionally intermediate compound 16, which is anticipated to cyclize into 5-(2,2-dicyano-1-phenylvinyl)-2,5-dihydro-2-aminothiophene-3-carbonitrile derivatives 17a-c.
This interesting work shows that exactly the right purified solution of linear organic molecules can cyclize under the right conditions to present activated nucleotides.
A diepoxide is also formed that will cyclize and generate the THF-diol that we identified from corncob bedding (Mani et al.
To further enhance the antigenicity of these peptides, later work may include introducing several constraints to these peptides to increase structural rigidity, such as by adding linkers to cyclize the linear peptides or disulfide bonds for peptide stabilization.
At 240|degrees~C the pendant vinyl groups will begin to cyclize thermally with no peroxide, but for any temperature below, a high temperature peroxide is required.
n] species with a varying number of sulfur atoms until the number of sulfur atoms reaches eight, at which point the sulfur molecules cyclize and precipitate.
The P450-dependent hydroxylation of the methoxy group yields an intermediate corresponding to the hemiacetal of formaldehyde that can cyclize to form a methylenedioxy bridge via an ionic mechanism involving the methylene oxonium ion intermediate.
Four molecules of this porphyrin precursor cyclize and undergo several side-chain modifications to yield the tetrapyrrole protoporphyrin.
Methadone is extensively metabolized by hydroxylation and dealkylation of the nitrogen methyl groups; these dealkylated metabolites are unstable and spontaneously cyclize to form 2-ethylene1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP), which may further N-demethylate (1).
The amide intermediate then cyclize via internal nucleophilic attack by nitrogen is followed by elimination of water to give the target 3-isoindolo-2-yl-2-substituted quinazolin4(3H)-one (1-3) in substantial yield (Table-1)