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cyclooxygenase-2

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Noun1.cyclooxygenase-2 - an enzyme that makes prostaglandins that cause inflammation and pain and fever; "the beneficial effects of NSAIDs result from their ability to block Cox-2"
Cox-2
Cox, cyclooxygenase - either of two related enzymes that control the production of prostaglandins and are blocked by aspirin


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? Mentioned in ? References in periodicals archive
 
Lead-induced downregulation of soluble guanylate cyclase in isolated rat aortic segments mediated by reactive oxygen species and cyclooxygenase-2.
Renal and neurologic effects of cadmium, lead, mercury, and arsenic ... by Bernard, Alfred / Environmental Health Perspectives
Further, the company confirmed that agaro-oligosaccharide can inhibit the generations of cyclooxygenase-2 (COX-2) and prostaglandin E synthase, two enzymes required in the synthesis of prostaglandin E2 (PGE2), which is responsible for inducing inflammation and pains.
Takara Bio Sheds Light on Anti-inflammatory Mechanism of ... by JCNN News Summaries
These compounds, which inhibit the inflammatory enzyme cyclooxygenase-2, or COX-2, are currently used to treat pain and arthritis.
Anti-inflammatories' cancer effects vary by brand and tissue type by Harder, B. / Science News
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