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cyclooxygenase-2 |
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Lead-induced downregulation of soluble guanylate cyclase in isolated rat aortic segments mediated by reactive oxygen species and cyclooxygenase-2. Further, the company confirmed that agaro-oligosaccharide can inhibit the generations of cyclooxygenase-2 (COX-2) and prostaglandin E synthase, two enzymes required in the synthesis of prostaglandin E2 (PGE2), which is responsible for inducing inflammation and pains. These compounds, which inhibit the inflammatory enzyme cyclooxygenase-2, or COX-2, are currently used to treat pain and arthritis. |
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