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cyclophosphamide

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
cy·clo·phos·pha·mide  (skl-fsf-md)
n.
A highly toxic, immunosuppressive, antineoplastic drug, C7H15Cl2N2P, used in the treatment of Hodgkin's disease, lymphoma, and certain other forms of cancer, such as leukemia and breast cancer.

cyclophosphamide [ˌsaɪkləʊˈfɒsfəˌmaɪd]
n
(Medicine / Pharmacology) an alkylating agent used in the treatment of leukaemia and lymphomas
[from cyclo- + phosph(orus) + amide]


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The treatment of choice is chemotherapy, which usually includes cyclophosphamide, vincristine, and prednisone.
ovatus) were pooled and intraperitoneally injected into 15 ddY male mice (6-15 pooled ticks per mouse) treated with the immunosuppressant cyclophosphamide.
Pharmacokinetic studies suggested a significant decrease in cyclophosphamide clearance, but no obvious affects on the other drugs.
 
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