cyclophosphamide


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Related to cyclophosphamide: vincristine

cy·clo·phos·pha·mide

 (sī′klə-fŏs′fə-mīd′)
n.
A cytotoxic, immunosuppressive, antineoplastic drug, C7H15Cl2N2O2P, used in the treatment of Hodgkin and non-Hodgkin lymphomas and various other forms of cancer, including multiple myeloma, breast cancer, and certain types of leukemia.

cyclophosphamide

(ˌsaɪkləʊˈfɒsfəˌmaɪd)
n
(Pharmacology) an alkylating agent used in the treatment of leukaemia and lymphomas
[C20: from cyclo- + phosph(orus) + amide]
Translations

cy·clo·phos·pha·mide

n. ciclofosfamida, droga antineoplástica usada también como inmunosupresor en trasplantes.

cyclophosphamide

n ciclofosfamida
References in periodicals archive ?
Intravenous pulse cyclophosphamide treatment of severe lupus nephritis: a prospective five-year study.
In 2006, trastuzumab gained approval in a regimen containing doxorubicin, cyclophosphamide, and paclitaxel for adjuvant treatment.
A standard dose of REOLYSIN(R) is administered intravenously over five consecutive days, while an intravenous dose of cyclophosphamide is administered three days before REOLYSIN(R) treatment and continues through the course of the treatment cycle.
We describe such a case and highlight the use of cyclophosphamide as adjunctive therapy to steroids and plasma exchange.
Taking a somewhat different approach to this question Of whether to combine HAART with therapy for ARL, our group at the National Cancer Institute has explored the use of infusional dose-adjusted EPOCH (etoposide, doxorubicin, vincristine, cyclophosphamide, and prednisone) chemotherapy in ARL with HAART temporarily withheld during the period of EPOCH treatment.
Cyclophosphamide is a compound used in treating cancer to suppress the immune system and has been used to tackle a variety of cancers, most commonly Hodgkin's disease and some cases of children's leukaemia.
The Phase 2 open-label, single-arm, Simon 2-Stage breast cancer trial was designed to determine if preoperative administration of NOV-002 in combination with doxorubicin and cyclophosphamide followed by docetaxel (AC-T) results in at least a doubling in the rate of pathologic complete response (pCR) compared to a historical control.
Key words: chronic lymphocytic leukemia, thrombocytopenia, T cell, chemotherapy, chlorambucil, cyclophosphamide, avian, green-winged macaw, Ara chloroptera
They investigated the effects of routinely used doses of cyclophosphamide and fluorouracil, paclitaxel and doxorubicin.
The pre-planned three-year interim analysis of a randomised, prospective trial (known as FinXX) compared adjuvant capecitabine in combination with docetaxel and cyclophosphamide plus epirubicin for the treatment of early breast cancer with the standard, non-capecitabine regimen (docetaxel, epirubicin, cyclophosphamide and fluorouracil).
Higher disease activity, treatment with cyclophosphamide, older age, and a certain ethnic background were each linked with a significantly increased risk for developing premature gonadal failure in a study of 316 women with systemic lupus erythematosus.
Richard Vile of the Mayo Clinic College of Medicine in Rochester, Minnesota, published the results of its work testing the antitumor efficacy and safety of various combinations of reovirus and cyclophosphamide in vivo.