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He was also given oral cyclosporin 25mg TDS and minocycline 100mg daily but without any significant response.
Cyclophilin inhibitors are cyclosporin, which has been around since 1971 after it was first isolated from the fungus Tolypocladium inflatum, or cyclosporin derivatives.
Patients with hepatotoxicity episodes had a high total mortality rate, higher incidence of positive pre-transplant cytomegalovirus (CMV) IgM test, higher creatinine values during the first month post-transplant, underwent additional acute rejection episodes, and received fewer cyclosporin A based ID.
Caffeic acid phenethyl ester protects against oxidative stress-related renal dysfunction in rats treated with cyclosporin A.
They focused on the immunosuppressive drug cyclosporin A, which is widely used in the treatment of severe dry eye disease.
In the clinical trial, the team are now investigating how drug cyclosporin could limit heart damage after a heart attack by suppressing the activation of T-lymphocytes, stopping them from travelling into the heart muscle and damaging it.
The present paper reports successful treatment of perianal fistula in dogs with cyclosporin and ketoconazole.
Effect of cyclosporin A on apoptosis and expression of p53 and bcl-2 proteins in the gingiva of renal transplant patients.
Double-masked trial of cyclosporin versus colchicines and long-term open study of cyclosporin in Behcet\'s disease.
The influence of chlorexidine in the severity of cyclosporin A-induced gingival overgrowth.
Quantification is performed with cyclosporin D as an internal standard for cyclosporin A (Eton Biosciences) and ascomycin (Calbiochem) as an internal standard for sirolimus and tacrolimus (Eton Biosciences) (4).