cyclosporine


Also found in: Medical, Encyclopedia, Wikipedia.

cy·clo·spor·ine

 (sī′klə-spôr′ēn, -ĭn) also cy·clo·spor·in (-ĭn) or ci·clo·spor·in
n.
An immunosuppressive drug obtained from the soil fungus Tolypocladium inflatum, used to prevent the rejection of transplanted organs.

cy•clo•spo•rine

(ˌsaɪ kləˈspɔr in, -ɪn, -ˈspoʊr-, ˌsɪk lə-)

also cy•clo•spo•rin

(-ɪn)

n.
a product of certain soil fungi that suppresses immune reactions by disabling helper T cells, used esp. for minimizing rejection of transplants.
[1975–80; < New Latin Cyclospor(eae) a class of brown algae (see cyclo-, -spore) + -in1]
Translations

cy·clo·spor·ine

n. ciclosporina, agente inmunosupresivo usado en tranplantes de órganos.

cyclosporine, ciclosporin

(INN) n ciclosporina
References in periodicals archive ?
Whole blood cyclosporine was determined by RIA (Incstar) and whole blood tacrolimus by fluorescence polarization immunoassay (Abbott).
Immunosuppressive therapy was cyclosporine (100 mg twice a day) and prednisone (10 mg once a day).
In test tubes, normally slow-growing lung cancer cells that were exposed to cyclosporine developed hallmarks typical of more aggressive cancer cells.
In patients taking Rapamune with cyclosporine, decreased kidney function has been observed.
1, ATC Code: L04AD01, Generic Name: Cyclosporine, pharmaceutical form: Tablets / capsules Strength: 10 mg, Unit Value: 0.
Patients with severe, refractory interstitial cystitis may benefit from immunosuppressive therapy with cyclosporine, according to several studies.
WASHINGTON -- Perinatal outcomes were slightly, but not significantly, better in renal transplant recipients who were, immunosuppressed with cyclosporine, compared with those given azathioprine, according to findings from a study involving 59 pregnant women at a single research center.
Astellas says in a Phase 3 study conducted in Europe, 314 patients received a regimen of antibody induction, corticosteroids and azathioprine in combination with Prograf or cyclosporine modified for 18 months.
BERLIN, February 6 /PRNewswire/ -- A new study published in this month's issue of the Journal of the American Society of Nephrology shows that the risk of cancer in kidney transplant recipients was reduced by more than 50% at five years post transplantation in those patients who were treated with sirolimus following withdrawal of cyclosporine at three months.
The recommended specimen for measuring cyclosporine concentrations is whole blood anticoagulated with EDTA (1).
To prevent rejection of the myoblasts, which are obtained from healthy male donors, the team gave the boys the immunosuppressant drug cyclosporine.
USA, developing Mitogard[R], the only cyclosporine formula designed for CSF delivery, to treat amyotrophic lateral sclerosis.