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 (sī′klə-spôr′ēn, -ĭn) also cy·clo·spor·in (-ĭn) or ci·clo·spor·in
An immunosuppressive drug obtained from the soil fungus Tolypocladium inflatum, used to prevent the rejection of transplanted organs.


(ˌsaɪ kləˈspɔr in, -ɪn, -ˈspoʊr-, ˌsɪk lə-)

also cy•clo•spo•rin


a product of certain soil fungi that suppresses immune reactions by disabling helper T cells, used esp. for minimizing rejection of transplants.
[1975–80; < New Latin Cyclospor(eae) a class of brown algae (see cyclo-, -spore) + -in1]


n. ciclosporina, agente inmunosupresivo usado en tranplantes de órganos.

cyclosporine, ciclosporin

(INN) n ciclosporina
References in periodicals archive ?
Group E was injected acute nephrotoxic regimen of cyclosporine and amphotericin B infusion.
M2 PHARMA-October 20, 2017-Imprimis Pharmaceuticals to Offer Compounded Cyclosporine Alternative to Restasis
CYCLOSPORINE IS MORE cost effective than prednisolone for treating patients with large pyoderma gangrenosum lesions, based on data from a multicenter, randomized trial published online in the British Journal of Dermatology.
Background and Objective: Cyclosporine A (CsA), is a powerful immunosuppressant that has revolutionised the field of transplantation.
Both animals were treated with Cyclosporine (Neoral (a) soft capsules 100mg) at dose rate of 2.
0) and cyclosporine concentration was <25 ng/mL.
Objectives: To compare new onset dyslipidaemia in live-related renal transplant recipients taking cyclosporine versus tacrolimus after 3 months of therapy.
Cyclosporine (CsA) is extracted from Tolypocladium inflatum Gams, which is metabolized through the superfamily of hepatic isoenzymes P-450.
As for cyclosporine, more than 20 years of pregnancy registry data on organ transplant recipients treated with the drug--who are on higher doses than used in psoriasis--indicate that cyclosporine is a "viable drug to be used during pregnancy if absolutely necessary" he said.
The clinical trial by Florida ophthalmologists randomized 37 patients with ocular rosacea to twice-daily topical cyclosporine 0.
An order for "cycloprine 10 mg po qhs" which was intended to refer to the muscle relaxant cyclobenzaprine, was entered into a pharmacy system as "cyclosporine 10 mg po qhs" Fortunately, the error was caught, and cyclosporine was not dispensed.
Zortress is to be given in combination with reduced doses of the calcineurin inhibitor (CNI) cyclosporine, as well as vasiliximab and corticosteroids.