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Related to cytokine: Cytokine storm


Any of various proteins, such as the interleukins and lymphokines, that are released by cells of the immune system and act in intercellular communication, especially in regulating inflammation and the immune response.

[cyto- + Greek kīnein, to move; see kinin.]


(Biochemistry) any of various proteins, secreted by cells, that carry signals to neighbouring cells. Cytokines include interferon
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.cytokine - any of various protein molecules secreted by cells of the immune system that serve to regulate the immune system
protein - any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
TNF, tumor necrosis factor, tumour necrosis factor - a proinflammatory cytokine that is produced by white blood cells (monocytes and macrophages); has an antineoplastic effect but causes inflammation (as in rheumatoid arthritis)
lymphokine - a cytokine secreted by helper T cells in response to stimulation by antigens and that acts on other cells of the immune system (as by activating macrophages)
References in periodicals archive ?
Long term, however, cytokine activity that accompanies inflammation and chronic infection can lead to depression and other psychological illnesses.
MIAMI BEACH -- Elevated levels of the same cytokine were seen in three serious mental illnesses, but each illness had separate and distinct patterns of inflammatory markers, according to a study of immune function and mental illness.
Samples of gum and cheek tissue, known as oral mucosal transudate, taken that same day showed that those who experienced more of these positive emotions, especially awe, wonder and amazement, had the lowest levels of the cytokine, Interleukin 6, a marker of inflammation.
This flood of inflammatory molecules, known as a cytokine storm, is thought to contribute to flu-related deaths in humans.
These cytokines have the capacity to be bound by the cytokine receptors on the targeted cells.
Suppressors of cytokine signalling (SOCS) molecules control the flow of chemical messages inside cells and were discovered by institute researchers in the 1990s.
Modulation of cytokine secretion may offer novel approaches in the treatment of a variety of diseases.
Ricerca Biosciences, an integrated preclinical pharmaceutical contract research organization (CRO), today announced the introduction of two new state-of-the-art cellular assay services: Early Safety Screening Cytotoxicity and ImmunoSIGNAL Cytokine Storm Cellular Assay.
The characteristics of knee synovial fluid have been defined for immunoglobins, glucose, fibrous cartilage, uric acid, and other proteins, yet little work has investigated cytokine levels in non-rheumatologic joint conditions.
The method includes the steps of immunizing an animal with a cytokine receptor or portion of a cytokine containing the critical binding site which portion includes the extracellular domain 4 or analogous domain in the analogous common receptor or part thereof.
We do not know how long ago this virus emerged, how deadly it is, whether it has pandemic potential, how the severity of infection relates to patient age, and why some infected patients die-whether a cytokine storm is responsible for these deaths," he says.