(redirected from Cytokines)
Also found in: Thesaurus, Medical, Encyclopedia.


Any of various proteins, such as the interleukins and lymphokines, that are released by cells of the immune system and act in intercellular communication, especially in regulating inflammation and the immune response.

[cyto- + Greek kīnein, to move; see kinin.]


(Biochemistry) any of various proteins, secreted by cells, that carry signals to neighbouring cells. Cytokines include interferon
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.cytokine - any of various protein molecules secreted by cells of the immune system that serve to regulate the immune system
protein - any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
TNF, tumor necrosis factor, tumour necrosis factor - a proinflammatory cytokine that is produced by white blood cells (monocytes and macrophages); has an antineoplastic effect but causes inflammation (as in rheumatoid arthritis)
lymphokine - a cytokine secreted by helper T cells in response to stimulation by antigens and that acts on other cells of the immune system (as by activating macrophages)
References in periodicals archive ?
Cytokines, the chemicals that coordinate immune cells and amplify immune response, also affect the brain and cause behavioral changes.
Serious mental illness is associated with immune activation, and previous studies have found activation of various cytokines in many mental illnesses.
Researchers have linked positive emotions -- especially the awe we feel when touched by the beauty of nature, art and spirituality -- with lower levels of pro-inflammatory cytokines, which are proteins that signal the immune system to work harder.
Immune cells release cytokines to trigger an immune response that protects the body from infection.
Immune cells release signalling molecules called cytokines to trigger an immune response that protects the body from infection.
Interleukin-6 (IL-6) family cytokines are pleiotropic secreted factors that have been shown to play an important role in cancer metastasis, yet little is known about their role in the metastatic process of prostate cancer.
The most frequently studied cytokines were IL-1, IL-6, TNF, and IFN.
In this assay, compounds are evaluated for their ability to stimulate human peripheral blood mononuclear cells to secrete specific cytokines and chemokines.
Cytokines are low molecular weight glycoproteins produced by immune as well as non-immune cells which act as molecular signals for communication between cells of the immune system.
Biopharmaceutical company Immunomedics Inc (Nasdaq:IMMU) revealed on Tuesday the receipt of the US Patent 8,034,352, "Tetrameric cytokines with improved biological activity.
It is clear that inflammatory cytokines constitute a key link between periodontal disease and systemic disease.
Researchers also noted that asthma increases proinflammatory cytokines and therefore may play a role in the development of coronary artery disease.

Full browser ?