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cytolytic |
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Gene products of PVL (lukS-PV and lukF-PV), which are encoded by contiguously located, cotranscribed genes (lukS-PV and lukF-PV), assemble as hetero-oligomers and synergistically exert cytolytic pore-forming activity (1). The latter function has been described to involve a synergistic interaction between IL-1 and IL-6 on the induction of cytolytic T-lymphocyte responses (Akira et al. The other depends heavily on T cells -- not helper, but cytolytic CD8 T cells -- that can destroy tumors or cells infected with viruses or bacteria. |
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