Also found in: Thesaurus, Medical, Wikipedia.


Of, relating to, or producing pathological changes in cells.

cy′to·path′o·ge·nic′i·ty (-jə-nĭs′ĭ-tē) n.


causing cytopathy
ThesaurusAntonymsRelated WordsSynonymsLegend:
Adj.1.cytopathogenic - of or relating to or causing pathological changes in cells
unhealthful - detrimental to good health; "unhealthful air pollution"; "unhealthful conditions in old apartments with peeling lead-based paint"
Mentioned in ?
References in periodicals archive ?
Poliovirus/PVSRIPO causes drastic, rapid cytopathogenic effects leading to gross morphologic changes and cell detachment.
We infected cells in duplicate with 200 [mciro]L of stool extract, incubated at 36[degrees]C, and observed microscopically for cytopathogenic effect (CPE) daily for 5 days.
Viruses from the culture supernatants of 293A cells that showed cytopathogenic effects were purified by cesium chloride banding.
The analyses of the plaques (plaque-forming unit, PFU) and the cytopathogenic effect (CPE) were performed 3-6 days later.
The IBH-HPS virus was successfully adapted after three blind passages (Vero cell line) and the 4th passage was fully adapted as it gave cytopathogenic effect (CPE) in 48 h post infection in Vero cells.
The cells were then cultured for 7-10 days to induce cytopathogenic effect (CPE).
The influenza H1N1 was found to induce severe cytopathogenic effects in a dose-dependant manner, however the cells treated with RGE displayed decreased viral cytopathogenic effects and reduced cell death caused by the virus.
Cytopathogenic effect of poliomyelitis viruses in vitro on, human embryonic tissues.
The virus infected flasks were incubated at 37 C and 5 % CO2 examined under inverted microscope after every 24 hours to check cell monolayer and detect any cytopathogenic effect (CPE).
Viruses contaminationCells were observed by phase-contrast microscopy for cytopathogenic examination, operation in details was similar to Li et al.
The effects of the combination were compared to several positive controls (acyclovir, ribavirin and amantadine hydrochloride) and assessment of the effects was done by standard viral viability tests (plaque reduction assay, cytopathogenic assays, virus titrations, analysis of the viral proteins in virus-specific enzyme immunoassays, and haemagglutination tests).
Determination of virus-induced cytopathogenic effects and virus titres revealed that EPs[R] 7630 at concentrations up to 100 [micro]g/ml interfered with replication of seasonal influenza A virus strains (H1N1, H3N2), respiratory syncytial virus, human coronavirus, parainfluenza virus, and coxsackie virus but did not affect replication of highly pathogenic avian influenza A virus (H5N1), adenovirus, or rhinovirus.