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cytosine

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia, Hutchinson 0.03 sec.
cy·to·sine  (st-sn)
n. Abbr. C
A pyrimidine base, C4H5N3O, that is the constituent of DNA and RNA involved in base pairing with guanine.

[cyt(o)- + (rib)os(e) + -ine2.]

cytosine  (st-sn)
A pyrimidine base that is a component of DNA and RNA, forming a base pair with guanine. Chemical formula: C4H5N3O.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.cytosine - a base found in DNA and RNA and derived from pyrimidine; pairs with guanine
deoxyribonucleic acid, desoxyribonucleic acid, DNA - (biochemistry) a long linear polymer found in the nucleus of a cell and formed from nucleotides and shaped like a double helix; associated with the transmission of genetic information; "DNA is the king of molecules"
ribonucleic acid, RNA - (biochemistry) a long linear polymer of nucleotides found in the nucleus but mainly in the cytoplasm of a cell where it is associated with microsomes; it transmits genetic information from DNA to the cytoplasm and controls certain chemical processes in the cell; "ribonucleic acid is the genetic material of some viruses"
pyrimidine - any of several basic compounds derived from pyrimidine

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? Mentioned in ? References in periodicals archive
 
A substitution of cytosine for guanine, also located in VD 1, resulted in Gln instead of Glu at amino acid position 117, as found in genotype B and strain 6BC (numbering according to the ompA amino acid sequence of the C.
Intended as a research tool, the T790M quantitative mutation assay detects the presence of a mutant thymidine base in a background of normal cytosine bases at position 2369 of the EGFR gene.
Methylation of cytosines in cytosine--guanine (CpG) dinucleotides represents a critical epigenetic DNA modification affecting gene expression and cellular function (Bird 2002).
 
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