cytosine

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Related to cytosine arabinoside: Daunorubicin

cy·to·sine

 (sī′tə-sēn′)
n. Abbr. C
A pyrimidine base, C4H5N3O, that is the constituent of DNA and RNA involved in base-pairing with guanine.

[cyt(o)- + (rib)os(e) + -ine.]

cytosine

(ˈsaɪtəsɪn)
n
(Biochemistry) a white crystalline pyrimidine occurring in nucleic acids; 6-amino-2-hydroxy pyrimidine. Formula: C4H5N3O. See also DNA, RNA

cy•to•sine

(ˈsaɪ təˌsin, -ˌzin, -sɪn)

n.
a pyrimidine base, C4H5N3O, that is one of the fundamental components of DNA and RNA, in which it forms a base pair with guanine. Symbol: C
[< German Cytosin (1894); see cyto-, -ose2, -ine2]

cy·to·sine

(sī′tə-sēn′)
A base that is a component of DNA and RNA, forming a base pair with guanine.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.cytosine - a base found in DNA and RNA and derived from pyrimidine; pairs with guanine
deoxyribonucleic acid, desoxyribonucleic acid, DNA - (biochemistry) a long linear polymer found in the nucleus of a cell and formed from nucleotides and shaped like a double helix; associated with the transmission of genetic information; "DNA is the king of molecules"
ribonucleic acid, RNA - (biochemistry) a long linear polymer of nucleotides found in the nucleus but mainly in the cytoplasm of a cell where it is associated with microsomes; it transmits genetic information from DNA to the cytoplasm and controls certain chemical processes in the cell; "ribonucleic acid is the genetic material of some viruses"
pyrimidine - any of several basic compounds derived from pyrimidine
Translations
Cytosin
cytosine
cytozyna
References in periodicals archive ?
He was treated with high doses of chemotherapy, cytosine arabinoside (ara-C) and idarubicin.
8] Nonstandard abbreviations: AML, acute myeloid leukemia; Ara-C, cytarabine (cytosine arabinoside); dCK, deoxycytidine kinase; Ara-CMP, cytosine arabinoside monophosphate; Ara-CTP, cytosine arabinoside triphosphate; FMNH2, reduced flavin mononucleotide; IPTG, isopropyl [beta]-D-1-thiogalactopyranoside; A, absorbance; AP, alkaline phosphatase.
Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma.
This drug was found to be active in patients resistant to, or intolerant of interferon therapy, and was proven to be effective in newly diagnosed CML in a seminal trial (the IRIS trial), which compared imatinib mesylate to interferon alpha with low-dose cytosine arabinoside.
Some oncologists believe that the sorafenib-associated syndrome is the same as the drug eruption known as Ara-C syndrome, a painful erythematous palmar/plantar eruption seen in leukemia patients receiving intravenous treatment with cytosine arabinoside (Ara-C).
Synergistic action of Aplidin and cytosine arabinoside in vitro and in vivo against lymphoblastic leukaemia.
2] daily and 7 days of cytosine arabinoside by continuous infusion at 100 mg/[m.
The antiproliferative activity of these compounds was found to be comparable to that of known antitumor agents, including cisplatin, chromomycin, cytosine arabinoside and 5-fluorouracil.
He was placed on a chemotherapeutic regimen of daunorubicin and cytosine arabinoside (ARA-C) for remission induction of AML.