Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.


The internal framework of a eukaryotic cell, composed of protein filaments that provide structural support and drive the movement of the cell and its internal components, typically divided into three categories (microfilaments, intermediate filaments, and microtubules) based on the diameter and composition of the filaments.

cy′to·skel′e·tal (-ĭ-tl) adj.


(Biochemistry) a network of fibrous proteins that governs the shape and movement of a biological cell


(ˌsaɪ təˈskɛl ɪ tn)

a shifting lattice arrangement of structural and contractile components distributed throughout the cell cytoplasm, composed of microtubules, microfilaments, and larger filaments.
cy`to•skel′e•tal, adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.cytoskeleton - a microscopic network of actin filaments and microtubules in the cytoplasm of many living cells that gives the cell shape and coherence
anatomical structure, bodily structure, body structure, complex body part, structure - a particular complex anatomical part of a living thing; "he has good bone structure"
cytol, cytoplasm - the protoplasm of a cell excluding the nucleus; is full of proteins that control cell metabolism
References in periodicals archive ?
These twisty fibers (below, in yellow; cell's nucleus in magenta) are part of a cell's internal scaffolding known as the cytoskeleton.
NEW YORK, June 25, 2015 /PRNewswire/ -- There are today 251 companies plus partners developing 366 targeting actin cytoskeleton modulators drugs in 1471 developmental projects in cancer.
Objective: In bacteria, the rigid external cell wall (CW) and the intracellular actin-like (MreB) cytoskeleton are major determinants of cell shape.
The ATM compounds target the micro-filament component of the cancer cell's cytoskeleton and have been designed to combine with anti-microtubular drugs (taxanes, vinca alkaloids) to produce comprehensive and fatal destruction of the cancer cell cytoskeleton.
Rich in sulfated galactans derived from the Hypnea musciformis algae, this novel ingredient is said to protect the cytoskeleton by maintaining vimentin organization and preserving synthesis of the extracellular matrix proteins; as well as support the matrix network by stimulating the formation of collagen and fibrillin networks.
Given that cytoskeleton elements determine the elastic properties of the cell surface the Young's modulus was measured before and after the load function for the performed study.
Endothelial cells serve as mediators between systemic circulation and particular organs, and the cytoskeleton in turn is crucial to regulation of internal function in any cell.
The target of anti-Tm drugs is the protein, Tm5NM1, an integral part of the microfilament component of the cytoskeleton of a cell.
Cytoskeleton depolymerization of the microtubule system led to the collapse of extended vimentin intermediate filament bundles into short agglomerations with disordered distributions.
Then they burst out of the PV, completely destroying and dissolving the protein-based cytoskeleton of their host, freeing themselves to seek out and infect new host cells.
Following application of the silver nanoparticles to ethanol-exposed cells, the actin cytoskeleton shows marked improvements and cell-death does not occur.
of New York) assembles 22 articles on techniques reflecting recent advances in experimental tools for cytoskeleton research with emphasis on animal, plant, protist, and fungal model systems.