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dedifferentiate

   Also found in: Medical, Wikipedia 0.03 sec.
de·dif·fer·en·ti·a·tion  (ddf--rnsh-shn)
n. Biology
Regression of a specialized cell or tissue to a simpler, more embryonic, unspecialized form. Dedifferentiation may occur before the regeneration of appendages in plants and certain animals and in the development of some cancers.
dedif·fer·enti·ate v.
ThesaurusLegend:  Synonyms Related Words Antonyms
Verb1.dedifferentiate - lose specialization in form or function
develop - grow, progress, unfold, or evolve through a process of evolution, natural growth, differentiation, or a conducive environment; "A flower developed on the branch"; "The country developed into a mighty superpower"; "The embryo develops into a fetus"; "This situation has developed over a long time"
differentiate - become different during development; "cells differentiate"


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As in nonmalignant tumors, cells have lost their normal control, often dedifferentiate, and grow in an inappropriate place.
Dioxins and endometriosis: a plausible hypothesis. (Research Review) by Cummings, Audrey M. / Environmental Health Perspectives
Reprogramming an adult cell to dedifferentiate it back into pluripotent stem cells is a key proposal (Option 4) in the 2005 President's Council on Bioethics white paper "Alternative Sources of Human Pluripotent Stem Cells.
Germ Line Pluripotent Stem Cell Research Cited by Senator Coburn in ... by Business Wire
The most significant seems to be that the worms do not dedifferentiate cells to create the blastema.
Starting over: some animals can regenerate limbs or even most of ... by Travis, John / Science News
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