denaturant


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de·na·ture

 (dē-nā′chər)
tr.v. de·na·tured, de·na·tur·ing, de·na·tures
1. To change the nature or natural qualities of.
2. To render unfit to eat or drink without destroying usefulness in other applications, especially to add methanol to (ethyl alcohol).
3. Biochemistry
a. To cause the tertiary structure of (a protein) to unfold, as with heat, alkali, or acid, so that some of its original properties, especially its biological activity, are diminished or eliminated.
b. To cause the paired strands of (double-stranded DNA) to separate into individual single strands.
4. Physics To add nonfissionable matter to (fissionable material) so as to prevent use in an atomic weapon.

de·na′tur·ant n.
de·na′tur·a′tion n.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.denaturant - any substance that serves as a denaturing agent
substance - a particular kind or species of matter with uniform properties; "shigella is one of the most toxic substances known to man"
References in periodicals archive ?
The enzyme denaturant produced by the bacterial spores denatures the purified enzyme to decrease a concentration of the purified enzyme in residue remaining on the surface after application of the cleaning composition.
L'occupation israelienne est globale et envahit les manuels et programmes scolaires, les modes d'echanges commerciaux tout en denaturant l'histoire de la Palestine et du Moyen-Orient.
The liquid, chitosan-containing paint denaturant technology provides a more environmentally responsible alternative to traditional melamine-formaldehyde or acrylic acid-based chemistries.
Having met the requirements stated in the RoHS directive, Markem-Imaje has now taken on a new challenge to replace the methanol currently used as denaturant in its alcohol-based inks with isopropanol (IPA).
L'economie solidaire auriat laisse place a une pratique d'economie sociale assujettie aux principes du liberalisme marchand, denaturant ainsi la vocation politique du projet porte par les organisations d'economie solidaire francaises creees entre 1800 et 1850.
Methanol is commonly sold as automotive windshield washer fluid and can be found in paint strippers, carburetor cleaners, photocopying fluid, as an alcohol denaturant and in some canned cooking fuels such as Sterno[R].
PCR-amplified fragments are separated during electrophoresis according to their melting behavior on a polyacrylamide gel with a linearly increasing denaturant gradient.
An aliquot (15 [micro]L) of PCR sample was electrophoresed in a colinearly increasing double gradient of 50% to 95% denaturant (100% denaturant: 7 mol/L urea, 400 mL/L formamide) and 6.
The bands in position 4 actually consisted of two DNA fragments that comigrated in the 20-70% denaturant gradient gel.
Gladase uses papain, a proteolytic enzyme derived from papayas, and urea, a denaturant of proteins, to remove necrotic tissue and liquefy slough in acute wounds, chronic wounds, infected wounds, carbuncles, and burns.
Peoples Genetics' technologies are made up of procedures for sample preparation and constant denaturant capillary electrophoresis that can be applied to large pools of DNA (up to 100,000 samples) for identification and validation of low-frequency mutations.
The linear DGGE was performed in 8% polyacrylamide with 20% to 80% denaturant.