denature

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de·na·ture

 (dē-nā′chər)
tr.v. de·na·tured, de·na·tur·ing, de·na·tures
1. To change the nature or natural qualities of.
2. To render unfit to eat or drink without destroying usefulness in other applications, especially to add methanol to (ethyl alcohol).
3. Biochemistry
a. To cause the tertiary structure of (a protein) to unfold, as with heat, alkali, or acid, so that some of its original properties, especially its biological activity, are diminished or eliminated.
b. To cause the paired strands of (double-stranded DNA) to separate into individual single strands.
4. Physics To add nonfissionable matter to (fissionable material) so as to prevent use in an atomic weapon.

de·na′tur·ant n.
de·na′tur·a′tion n.

denature

(diːˈneɪtʃə) ,

denaturize

or

denaturise

vb (tr)
1. to change the nature of
2. (Chemistry) to change (a protein) by chemical or physical means, such as the action of acid or heat, to cause loss of solubility, biological activity, etc
3. (Chemistry) to render (something, such as ethanol) unfit for consumption by adding nauseous substances
4. (Nuclear Physics) to render (fissile material) unfit for use in nuclear weapons by addition of an isotope
deˈnaturant n
deˌnaturˈation n

de•na•ture

(diˈneɪ tʃər)

v.t. -tured, -tur•ing.
1. to deprive (something) of its natural character, properties, etc.
2. to render (various alcohols) undrinkable by adding an unwholesome substance.
3. to treat (a protein or the like) by chemical or physical means so as to alter its original state.
[1675–85]
de•na′tur•ant, n.
de•na`tur•a′tion, n.

denature


Past participle: denatured
Gerund: denaturing

Imperative
denature
denature
Present
I denature
you denature
he/she/it denatures
we denature
you denature
they denature
Preterite
I denatured
you denatured
he/she/it denatured
we denatured
you denatured
they denatured
Present Continuous
I am denaturing
you are denaturing
he/she/it is denaturing
we are denaturing
you are denaturing
they are denaturing
Present Perfect
I have denatured
you have denatured
he/she/it has denatured
we have denatured
you have denatured
they have denatured
Past Continuous
I was denaturing
you were denaturing
he/she/it was denaturing
we were denaturing
you were denaturing
they were denaturing
Past Perfect
I had denatured
you had denatured
he/she/it had denatured
we had denatured
you had denatured
they had denatured
Future
I will denature
you will denature
he/she/it will denature
we will denature
you will denature
they will denature
Future Perfect
I will have denatured
you will have denatured
he/she/it will have denatured
we will have denatured
you will have denatured
they will have denatured
Future Continuous
I will be denaturing
you will be denaturing
he/she/it will be denaturing
we will be denaturing
you will be denaturing
they will be denaturing
Present Perfect Continuous
I have been denaturing
you have been denaturing
he/she/it has been denaturing
we have been denaturing
you have been denaturing
they have been denaturing
Future Perfect Continuous
I will have been denaturing
you will have been denaturing
he/she/it will have been denaturing
we will have been denaturing
you will have been denaturing
they will have been denaturing
Past Perfect Continuous
I had been denaturing
you had been denaturing
he/she/it had been denaturing
we had been denaturing
you had been denaturing
they had been denaturing
Conditional
I would denature
you would denature
he/she/it would denature
we would denature
you would denature
they would denature
Past Conditional
I would have denatured
you would have denatured
he/she/it would have denatured
we would have denatured
you would have denatured
they would have denatured
ThesaurusAntonymsRelated WordsSynonymsLegend:
Verb1.denature - add nonfissionable material to (fissionable material) so as to make unsuitable for use in an atomic bomb
alter, change, modify - cause to change; make different; cause a transformation; "The advent of the automobile may have altered the growth pattern of the city"; "The discussion has changed my thinking about the issue"
2.denature - modify (as a native protein) especially by heat, acid, alkali, or ultraviolet radiation so that all of the original properties are removed or diminished
alter, change, modify - cause to change; make different; cause a transformation; "The advent of the automobile may have altered the growth pattern of the city"; "The discussion has changed my thinking about the issue"
3.denature - make (alcohol) unfit for drinking without impairing usefulness for other purposes
alter, change, modify - cause to change; make different; cause a transformation; "The advent of the automobile may have altered the growth pattern of the city"; "The discussion has changed my thinking about the issue"
Translations

denature

vtdenaturieren; (= make unfit for eating, drinking also)ungenießbar machen
References in periodicals archive ?
A cette strategie de denaturation de la realite du fait sahraoui, le representant sahraoui a oppose les verites historiques d'un mouvement de lutte de liberation nationale, internationalement reconnu conformement aux decisions 37/34 de 1979 et 19/35 de 1980 des Nations-unies.
In a nutshell, the HUNK measures a time-tested thermodynamic value, [eth]oG, using chemical denaturation.
Contract notice: Delivery of equipment fume hoods, machine staining cryostat microtome rotary water bath stations embedding tissue material, cabinets preparations cytological centrifuge, saw the autopsy, tissue processor, laboratory incubators, wash disinfection, the apparatus for denaturation and hybridization to department of human sciences.
Seule la justice est habilitee, par la force des choses, a notifier le dernier mot sur des dossiers qui ne tolerent plus immixtion ni denaturation.
Upon cooking, a distinct outer layer was observed, which resulted from protein denaturation and starch gelatinization.
Our coverage of the New York Attorney General's investigation into herbal supplement products offers several expert voices who agreed that DNA barcoding analysis is not a valid test method for identification of botanical extracts due to the loss or denaturation of DNA material during processing (pages 8 and 62).
oxytoca and EHEC/EPEC reactions were as follows: denaturation at 95[degrees]C for 5 minutes, followed by 35 cycles of denaturation at 94[degrees]C for 30 seconds, annealing at primer-specific temperature for 30 seconds, and extension at 72[degrees]C for 1 minute, and finally 72[degrees]C for 7 minutes.
0) with a 10 minute denaturation at 95[degrees]C followed by 45 cycles of denaturation at 95[degrees]C for 5 s, annealing at 52[degrees]C for 5 s, and extension at 72[degrees]C for 10 s, with a ramp rate of 20[degrees]C/s.
For minor and major DNA alleles, coamplification at lower denaturation temperature-PCR (COLDPCR) [1] selectively enriches minority alleles from mixtures of wild-type and mutation-containing sequences without a priori knowledge of the type or position of a mutation within a sequence (1).
The reaction proceeds by repeatedly cycling the reaction temperature between denaturation (95[degrees]-99[degrees]C) and a lower temperature suitable for sequence specific annealing and DNA ligase activity (depending on sequence composition and length of the primers, but generally in the 50[degrees]-60[degrees]C range).
For rrs, initial denaturation was at 95[degrees]C for 1 min, followed by 45 cycles of denaturation at 95[degrees]C for 30 s, annealing at 56[degrees]C for 30 s, and elongation at 68[degrees]C for 90 s for PCR and 70 s for nPCR, and then by a final extension step at 72[degrees]C for 7 min.
The long soaking treatment in acidic lime juice, the boiling in water and the drying with a high temperature during the process of making mangrove Avicennia marina fruit flour results in the denaturation of proteins.