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Noun1.deoxyadenosine - a nucleoside component of DNA; composed of adenosine and deoxyribose
nucleoside - a glycoside formed by partial hydrolysis of a nucleic acid
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2,3 The positive interaction between gemcitabine and radiotherapy is likely due to a combination of mechanisms that include deoxyadenosine triphosphate depletion, cell cycle redistribution and inhibition of DNA synthases and repair.
MDA reacts with deoxyadenosine and deoxyguanosine in DNA, forming DNA MDA and other thiobarbituric acid reactive substances (TBARS) condense with two equivalents of thiobarbituric acid to give a fluorescent red derivative.
TK is a key enzyme in the pyrimidine salvage pathway, catalyzing the transfer of the terminal phosphate from adenosine triphosphate to the 5'-hydroxyl group of thymidine, producing deoxyadenosine triphosphate, which is subsequently incorporated into DNA.
This enzyme irreversibly converts adenosine to inosine and deoxyadenosine to deoxyinosine, and the speed rate of this reaction gives an account of enzymatic activity, calculated as ADA concentration in the laboratory.
E-ADA is considered to be a key enzyme in the purine metabolism, catalyzing the irreversible deamination of adenosine and deoxyadenosine to inosine and deoxyinosine, respectively, and closely regulating extracellular adenosine and inosine concentrations (9,10).
In pyrosequencing, the natural deoxyadenosine triphosphate (dATP) results in false signals because, like ribose adenosine 5'-triphosphate (rATP), it is a substrate for luciferase.
TA cloning is achieved by Taq DNA polymerase which has non-template-dependent terminal transferase activity which helps adding of a single deoxyadenosine (A) to the 3' ends of PCR products.
Adenosine deaminase (ADA), an enzyme of purine salvage and catabolic pathway deaminates adenosine and deoxyadenosine to form inosine and deoxy inosine respectively.
ABBREVIATIONS: bDNA = Branched DNA; DNA = Deoxyribonucleic Acid; dNTP = Deoxyribonucleotides; dATP = Deoxyadenosine Triphosphate; dCTP = Deoxycytidine Triphosphate; dGTP = Deoxyguanosine Triphosphate; dTTP = Deoxythymidine Triphosphate; FDA = Food and Drug Administration; FRET = Fluorescence Resonance Energy Transfer; MRSA = Methicillin Resistant Staph aureus; MTB = Mycobacterium tuberculosis; NASBA = Nucleic Acid Sequence Based Amplification; PCR = Polymerase Chain Reaction; PFGE = Pulsed-Field Gel Electrophoresis; RT-PCR = Reverse Transcription Polymerase Chain Reaction; Taq = Thermus aquaticus; TMA = Transcription-Mediated Amplification; VRE = Vancomycin Resistant Enterococcus.
Adenosine deaminase (ADA) is an enzyme in the purine salvage pathway that catalyses the conversion of adenosine and deoxyadenosine to inosine and deoxyinosine with the release of ammonia.
The commonly used cloning strategy utilizes the feature of Taq DNA polymerase to add a 3' overhanging deoxyadenosine residues in most of the PCR products (1).