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deoxyadenosine

   Also found in: Medical, Wikipedia 0.06 sec.
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Noun1.deoxyadenosine - a nucleoside component of DNA; composed of adenosine and deoxyribose
nucleoside - a glycoside formed by partial hydrolysis of a nucleic acid

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In the disease, the lack of ADA enzyme allows the buildup of 2' deoxyadenosine triphosphate, a chemical that is particularly detrimental to immune system cells, especially T cells.
The study authors concluded that "clofarabine is the first deoxyadenosine analog with promising activity in pediatric ALL, pediatric AML and adult acute leukaemia at doses that are well tolerated.
 
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