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depigmentation |
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The main clinical manifestations of the exposed subjects were similar to those found in other arsenic poisoning areas of the world (2,3,33), mainly including cutaneous depigmentation, hyperpigmentation, and hyperkeratosis and increased incidence of peripheral vascular disorder, peripheral neuropathy, and liver swelling (30,31). Didanosine is associated with the following side effects: pancreatitis, peripheral neuropathy, vision changes (retinal depigmentation or optic neuritis), nausea and diarrhea. Vitiligo is a disease of the pigment producing cells characterized by patchy depigmentation of the skin of the face and hands. |
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