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Related to desmoplasia: dysplasia, adenocarcinoma, anaplasia, linitis plastica


a. desmoplásico-a, causante de adherencias.
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They are separated by thin, hypocellular fibrous septa that lack ovariantype stroma or desmoplasia, as seen in MEST and CDC, respectively, or the myxoid, edematous stroma seen in oncocytoma with predominant tubulocystic pattern.
Summary: Pancreatic ductal adenocarcinoma (PDA) is characterized by a tumor microenvironment (TME) with high stromal desmoplasia, a reduction in vessel density, and poor perfusion, all instrumental in PDAs' observed resistance to chemotherapeutic intervention.
2007) reported that rats exposed prenatally to 25 [micro]g BPA/kg BW/day displayed a higher number of ductal hyperplasias associated with desmoplasia in adulthood.
Extracellular and Connective Tissue Components Background stroma Neuropil Neuroblastoma Desmoplasia Desmoplastic small cell tumor Myxoid Liposarcoma, embryonal rhabdomyosarcoma Calcifications Neuroblastoma, synovial sarcoma, and MNST Lymphoglandular Non-Hodgkin lymphoma bodies Other elements Neuronal cells Neuroblastoma, ectomesenchymoma Rhabdomyoblasts Rhabdomyosarcoma Cross-striations Rhabdomyosarcoma Blastema/ Nephroblastoma, pleuropulmonary epithelium blastoma Abbreviation: MNST, malignant nerve sheath tumor.
On postmortem examination, histologic sections of the cranium at the level of the mass showed marked desmoplasia around the neoplastic cells and extensive reactive bone remodeling with branching trabeculae of bone extending throughout the neoplasm in former areas of normal skull (Fig 4).
Patients were considered for surgery alone if they had favorable T1 to T3 tumors resected with clear margins and without adverse pathologic prognostic factors, including angiolymphatic invasion, desmoplasia, or perineural invasion.
In some invasive tumors, revascularization occurrs adjacent to a region of desmoplasia rich in HA.
What should be the impact of scar size or prominent stromal desmoplasia and stromal inflammation on determining size of the invasive component?
Desmoplasia, the fibrotic stromal reaction associated with most carcinomas, is characterized by the local deposition of different fibrillar collagen types and often correlates with adverse prognosis in carcinomas (4, 5).
Moreover, the stroma associated with hyperplastic ducts showed signs of desmoplasia and contained an increased number of mast cells, suggesting a heightened risk of neoplastic transformation.