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desmosome
(redirected from desmosomal)

   Also found in: Medical, Encyclopedia, Wikipedia 0.45 sec.
desmosome [ˈdɛsməˌsəʊm]
n
(Life Sciences & Allied Applications / Biology) Cytology a structure in the cell membranes of adjacent cells that binds them together


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The reversible TSE observed here for C-cadherin provides support for the multiple conformations observed in desmosomal cadherins through electron tomography (84) and also suggest that the extracellular domains of cadherin molecules should not be considered as completely rigid units, even in the presence of Ca^sup 2+^.
Antibodies directed against desmosomal plaque proteins desmoplakins 1 and 2 have been described in a subset of patients with erythema multiforme major.
2) They are histologically characterized by suprabasilar acantholysis and immunopathologically characterized by autoantibodies to desmosomal cadherins.
 
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