diazoxide


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Noun1.diazoxide - vasodilator (trade name Hyperstat) used to treat severe hypertension
vasodilative, vasodilator - a drug that causes dilation of blood vessels
References in periodicals archive ?
The presentation reports the results of in vitro studies of three PKC activators, bryostatin, DCPLA and diazoxide, on their ability to correct the cholesterol transport defect in NPC1 cells.
Additive antinociceptive effect of the combination of diazoxide, an activator of ATP-sensitive [K.
In the study, ten non-diabetic subjects were given oral diazoxide, a drug that activates potassium channels in the hypothalamus.
The study found that the drug, diazoxide, acted on nerve cells in the mouse brain in ways that slowed the development of the neurodegenerative disorder.
Beneficial effect of diazoxide in obese hyperinsulinemic adults.
2 to ATP/ADP and to pharmacological agents, such as sulfonylurea and diazoxide, that close or open the [K.
1]-adrenoceptor antagonism, has not been widely available and thus the safest choice of intravenous agents has been limited primarily to hydralazine, with mini-dose diazoxide also used in some settings (3).
DCCR, diazoxide choline controlled release, is an ATP-dependent potassium channel agonist with potential utility in several cardiovascular and metabolic diseases.
In the myocytes, diazoxide a potassium channel opener (KCO), has approximately 2000-fold high affinity towards mito[K.
ATP] channel is normally activated by diazoxide (the main medical treatment for HI), resulting in channel opening, and ultimately, decreased insulin secretion.