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Noun1.diethylstilbesterol - synthetic nonsteroid with the properties of estrogen; formerly used to treat menstrual problems but was found to be associated with vaginal cancers in the daughters of women so treated during pregnancy
nonsteroid, nonsteroidal - an organic compound that does no contain a steroid
References in periodicals archive ?
Hsp90 and environmental impacts on epigenetic states: a model for the trans-generational effects of diethylstilbesterol on uterine development and cancer.
4 Despite BPA's having lower estrogenicity than estradiol, in in vivo studies its estrogenicity is only 100-fold lower than that of diethylstilbesterol (DES).
Diethylstilbesterol is 105 times more active than genistein, while daidzein is three-fourths as active as genistein, and so the estrogenic activity of soy isoflavones is usually thought to be minimal [34].
Drug companies began to synthesize female hormones in the 1940's and 50's, starting with very powerful and dangerous estrogens such its diethylstilbesterol (DES), and over time have produced more effective, safer and lower potency estrogens and progestins, mainly for use in birth control.
Chemicals that are known endocrine disruptors include diethylstilbesterol (the drug DES), dioxin and dioxin like compounds, PCBs, DDT, and some other pesticides.