Today, succimer is used most often for chelation, although calcium disodium EDTA and dimercaprol
are still used in some cases.
Researchers have now found that the drug, dimercaprol
, removes the toxin by attacking certain chemical features of acrolein, neutralizing it for safe removal by the body.
anti-Lewisite or dimercaprol
, and ethylenediaminetetraacetic acid.
Different chelating agents are used for particular metals although there are also pluripotent agents such as dimercaprol
, aminophenoxyethane-acetic acid (BAPTA), deferoxamine, Ca, [Na.
Edetate calcium disodium, dimercaprol
, and penicillamine are examples of commonly used chelation agents.
Copper chelators can be used in severe poisoning like dimercaprol
, D-penicillamine, British Anti-Lewisite (BAL), Ethylene Diamine Tetra Acetate (EDTA).
Chelating agents such as edetate calcium disodium (EDTA), sodium 2, 3-dimercaptopropane sulfonate (DMPS), and dimercaprol
(BAL) have been reported (Table 1) [7-10].
There are six agents available to treat heavy metal (arsenic, gold, iron, lead, and mercury) intoxication: de-ferasirox (iron), deferoxamine (iron), dimercaprol
(arsenic, gold, lead, and mercury), edetate calcium disodium (lead), penicillamine (copper and mercury), and succimer (lead).
BAL (British Anti Lewisite), dimercaprol
, acido 2,3dimercaptopropanol.
En los casos de encefalopatia plumbica y pacientes plombemia mayor a 100 ([micron]/dL debe asociarse Dimercaprol
Mas de cinco quelantes del plomo se han identificado desde entonces y el dimercaprol
es el mas importante.
In addition, elemental (metallic) mercury can easily enter systemic circulation directly via the skin or inhalation of mercury vapors via the alveoli (7) Universally, chelating agents, including dimercaptosuccinic acid (DMSA), dimercaprol
(BAL), and 2,3-dimercaptopropane-1-sulphonate (DMPS), are used to treat mercury intoxication (1).