dissociation constant


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Noun1.dissociation constant - the equilibrium constant for a reversible dissociation
equilibrium constant - (chemistry) the ratio of concentrations when equilibrium is reached in a reversible reaction (when the rate of the forward reaction equals the rate of the reverse reaction)
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Implementing various physical chemistry concepts to explain physiological phenomena has led to an understanding that the dissociation constant of a drug--receptor complex ([K.
21 [30] where, Ka is the dissociation constant of H2BrO +.
where, R is the gas constant, T is the absolute temperature and K is the same as the solubility-product constant for water-insoluble compound or the dissociation constant for cation-chelate.
The dissociation constant was calculated from the binding constant ([K.
The proposed approach will result in the measurement of a dissociation constant for specific drug-membrane combinations.
If we apply a very dilute analyte solution, the dissociation constant becomes proportional to the reciprocal of retardation (Eq.
m1] is the Michaelis constant for PDE activity, [I] is the concentration of PDE inhibitor, KI is the inhibitor dissociation constant, [k.
With such as dramatic difference in fluorescence lifetimes, we have been able to determine ALDH2 enzyme activity, the steady state NADH-ALDH2 complex concentration, the rate of rate of NADH displacement from NADH-ALDH2 complex and the dissociation constant for NADH with ALDH2 under a wide range of magnesium ion concentrations.
The accumulation of a weak acid in the bacterial cytosol--the internal fluid of the cell--will result in acid dissociation if the acid dissociation constant (pKa) is lower than the intracellular pH.
The four levels of the enzyme saturation with substrate S (S stands for PEP in this particular case) can be presented by the following schemes, where the substrate interaction with the first subunit is quantified by the dissociation constant K, affinity for the second substrate molecule is quantified by [alpha]K, and affinity for the third and fourth substrate molecules by [beta]K and [gamma]K, respectively [14].