dissociation constant


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Related to dissociation constant: equilibrium constant, dissociation constant of water, Acid dissociation constant
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Noun1.dissociation constant - the equilibrium constant for a reversible dissociation
equilibrium constant - (chemistry) the ratio of concentrations when equilibrium is reached in a reversible reaction (when the rate of the forward reaction equals the rate of the reverse reaction)
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The proposed approach will result in the measurement of a dissociation constant for specific drug-membrane combinations.
m1] is the Michaelis constant for PDE activity, [I] is the concentration of PDE inhibitor, KI is the inhibitor dissociation constant, [k.
We fitted corrected titration data for BL22P1B11 with a single-site binding model to determine the equilibrium dissociation constant ([K.
With such as dramatic difference in fluorescence lifetimes, we have been able to determine ALDH2 enzyme activity, the steady state NADH-ALDH2 complex concentration, the rate of rate of NADH displacement from NADH-ALDH2 complex and the dissociation constant for NADH with ALDH2 under a wide range of magnesium ion concentrations.
The accumulation of a weak acid in the bacterial cytosol--the internal fluid of the cell--will result in acid dissociation if the acid dissociation constant (pKa) is lower than the intracellular pH.
The four levels of the enzyme saturation with substrate S (S stands for PEP in this particular case) can be presented by the following schemes, where the substrate interaction with the first subunit is quantified by the dissociation constant K, affinity for the second substrate molecule is quantified by [alpha]K, and affinity for the third and fourth substrate molecules by [beta]K and [gamma]K, respectively [14].
A dissociation constant of 58 nM for a region of the insulin enhancer element was determined by the electrophoretic mobility shift assay.
Removal of the hydroxyl group of Tyr6 has no effect on the dissociation constant for glutathione.
The resulting data demonstrated a close relationship between the apparent acid dissociation constant, or pKa, of the ionizable amino lipid head groups present in the LNPs and their ability to elicit potent hepatic gene silencing in vivo.