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disulfiram

   Also found in: Medical, Encyclopedia, Wikipedia, Hutchinson 0.02 sec.
di·sul·fi·ram  (d-slf-rm)
n.
A drug used in the treatment of alcoholism that interferes with the metabolic degradation of alcohol, producing an unpleasant reaction when even a small quantity of alcohol is consumed.
[disulfi(de) + (thiu)ram, chemical name (thi(o)- + ur(ea) + am(ide)).]
disulfiram [ˌdaɪsʌlˈfɪərəm]
n
(Medicine / Pharmacology) a drug used in the treatment of alcoholism that acts by inducing nausea and other unpleasant effects following ingestion of alcohol
[from tetraethylthiuram disulfide]
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.disulfiramdisulfiram - a drug (trade name Antabuse) used in the treatment of alcoholism; causes nausea and vomiting if alcohol is ingested
Antabuse
medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease


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? Mentioned in ? References in periodicals archive
 
Effect of chronic disulfiram administration on the activities of CYP1A2, CYP2C19, CYP2D6, CYP2E1, and N-acetyltransferase in healthy human subjects.
Occupational toluene exposure induces cytochrome P450 2E1 mRNA ... by Albores, Arnulfo / Environmental Health Perspectives
An index for assessing blindness in a multi-centre clinical trial: disulfiram for alcohol cessation--a VA cooperative study.
Participant blinding and gastrointestinal illness in a randomized, ... by Levy, Deborah A. / Emerging Infectious Diseases
Important interactions between Kaletra and other agents, including rifabutin (Mycobutin), disulfiram (Antabuse), metronidazole (Flagyl), methadone (Dolophine) and corticosteroids, may require adjusted dosing of either drug and are noted in Kaletra's package insert.
LOPINAVIR/RITONAVIR (Kaletra) by Research Initiative/Treatment Action!
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