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| The drug, drotrecogin alfa (activated) (APC) is a genetically engineered version of a naturally occurring human protein that interferes with some of the body's harmful responses to severe infection, including the formation of blood clots that can lead to organ failure and death. In addition to the ADDRESS (Administration of Drotrecogin alfa (activated) in Early Severe Sepsis) trial investigating the use of Xigris in lower-risk patients, Lilly is undertaking trials of Xigris in children with severe sepsis, and investigating the concomitant use of low-dose heparin with Xigris. In addition to the ADDRESS (Administration of Drotrecogin alfa (activated) in Early Severe Sepsis) trial investigating the use of Xigris in lower-risk patients, Lilly is undertaking trials of Xigris in children with severe sepsis, and investigating the concomitant use of low-dose heparin with Xigris. |
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