The differential diagnosis of granulomatous mastitis includes breast cancer, infectious process (bacterial, fungal, or parasitic abscess), autoimmune disease (Wegener's vasculitis, giant cell arteritis), duct ectasia
, other rare causes linked with systemic disease (diabetes mellitus, sarcoidosis), and idiopathic granulomatous mastitis.
2] These include all non-malignant conditions like fibroadenoma, fibrocystic disease, mastalgia, mammary duct ectasia
, sclerosing adenosis, lactational adenoma, benign phyllodes tumour, intraductal papilloma, fibrous disease, blunt duct adenosis, calcification, breast abscess, lactational mastitis, puerperal mastitis, granulomatous lobular mastitis, fat necrosis, tuberculous mastitis, galactocele, gynaecomastia and lipoma.
occurs when a retroareolar duct fills with fluid.
In mammary duct ectasia
(MDE), the periductal inflammation is the principal pathological expression.
The final histopathology showed intraductal papilloma 13 (36%), duct ectasia
18(50%), DCIS 1 (2.
Pancreatic heterotopia in the duodenal wall may be present because of incomplete involution of the dorsal pancreatic head, (16) with secondary, localized inflammation, cicatrization, cystic dystrophy, and duct ectasia
Inflammatory disease of the breast fall into two general categories, lactational infections and chronic subareolar infections associated with duct ectasia
Once more common causes of unilateral breast swelling are excluded, less common etiologies, such as duct ectasia
, mammary adenosis or fat necrosis, and blunt force trauma, should be considered.