The concept of fat emulsion dated back to the 1960s when hospitals in advanced countries found soy bean oil with its oleic acid and linoleic acid to be an ideal component of intravenous nutrition for critically ill patients like those who suffer from serious burn or advanced tumor and dyscrasia
or those who had car accident or major surgery.
Flow cytometry showed no evidence of hematopoietic neoplasia, lymphoproliferative disease, or plasma cell dyscrasia
POEMS syndrome is a underlying plasma cell dyscrasia
related paraneoplastic syndrome and CD is one of the major criteria in the diagnosis of this disease.
What type of plasma cell dyscrasia
is associated with these results?
In addition, SLE and SS are also associated with some plasma cell dyscrasias
, such as monoclonal gammopathy of undetermined significance, macroglobulinemia, and amyloidosis; however, multiple myeloma (MM) as a lymphoproliferative neoplasm and plasma cell dyscrasia
are not nearly as common.
Mean age, y 52 Sex Men 194 (52) Women 179 (48) Clinical presentation Neurologic symptoms 291 (78) Hematologic malignancy, % of all cases 115 (31) Mature B-cell lymphoma, % of 78 (68) hematologic malignancies Primary central nervous system B-cell 8 (8) lymphoma, % of hematologic malignancies Natural killer/T-cell lymphoma, % of 12 (10) hematologic malignancies Hodgkin lymphoma, % of 6 (5) hematologic malignancies B-cell acute lymphoblastic leukemia, 4 (3) % of hematologic malignancies T-cell acute lymphoblastic leukemia, 4 (3) % of hematologic malignancies Plasma cell dyscrasia
, % of 3 (3) hematologic malignancies Immunosuppressed 45 (12) Brain imaging 347 (93) Abnormal findings 179 (51) Flow cytometry samples 501 (100) Cytology samples 424 (85) Brain biopsy samples 65 (13) Table 2.
27) Chloramphenicol is contraindicated in patients with blood dyscrasia
(blood disorders affecting red blood cells or platelets) and those with a family history of blood dyscrasia
, owing to a rare but serious side effect, aplastic anaemia, which may develop weeks or months after treatment has stopped.
Amyloidosis of the tongue as a paraneoplastic marker of plasma cell dyscrasia
Most cases of plasma cell dyscrasia
are diagnosed without Flow cytometry; however, it may be useful in certain patients with hematologic abnormalities and an elevated level of plasma cells in the bone marrow and without specific clinical manifestations (3).
She presented with an acute onset of a liver dyscrasia
that moderated only somewhat after four days.
POEMS is a rare syndrome which is associated with monoclonal plasma cell dyscrasia
major haemoptysis, bronchus Ca 2 Neurological Delirium/acute confusional state 2 Stroke 4 Severe peripheral neuropathy 7 Epilepsy 1 Cerebral palsy 1 Psychiatric Alcoholism/substance abuse 6 Schizophrenia 4 Depression 5 Acute psychosis 2 Drug-induced complications Significant hearing impairment 12 Acute renal failure (drug-induced) 3 Cutaneous drug reaction 3 Drug-induced hepatitis 1 Hypothyroidism owing to para-aminosalicylic acid 3 Miscellaneous Diabetes mellitus 12 Deep-vein thrombosis 3 Hypertension 3 Vasculitis 2 Arthritis 3 Miscellaneous (fractures, blood dyscrasia
, chronic 4 otitis media) Pressure sores 1 * Some patients had several comorbidities.