It is a nucleophile able to trap electrophilic
mutagens in lipophilic compartments and generates a metabolite that facilitates natriuresis.
6) GSTs function to detoxify electrophilic
toxicants, including those found in cigarette smoke, by facilitating conjugation to GSH.
Stephan's presentation was titled "From Frustrated Lewis Pairs to Electrophilic
Phosphonium Cations: Metal-free Approaches to Hydrogenation Catalysis.
water resistant) and energetically stable to corrosive, nucleo-, and electrophilic
attack from many polar moieties; (ii) resistant to ultraviolet (UV) light, and thus stable in intense sunlight over several decades; and (iii) fire resistant, so capable of surviving brief, but direct, exposure to flames.
The acceptor number--A quantitative empirical parameter for the electrophilic
properties of solvents.
In this proposal, we aim to develop first applications for two, previously very little explored non-covalent interactions that are based on electrophilic
halogen or chalcogen substituents ( halogen-bonds and chalcogen bonds ).
Polygodial also strongly activates another type of transient receptor channel, TRPA1 (transient receptor potential A1), a sensor for noxious and electrophilic
compounds and pungent natural products such as allyl isothiocyanate from mustard oil.
In this regard, our observation that another electrophilic
The presence of the electrophilic
[alpha]-methylene-[gamma]-lactone group is an important structural factor to induce apoptosis mediated by glutathione depletion of the cells.
However, modification of PAEK properties by the electrophilic
aromatic substitution polycondensation has received less attention to date.
fluorination using the Selectfluor" reagent was accomplished at two different points in the synthetic scheme, affording ring-selective fluorine incorporation into the sulfanilamide targets in yields ranging from 40-82%.
Nitroso and hydroxylamino functional groups are electrophilic
, and they can react with biomolecules.