The approval is based on results from the 8,442-patient PARADIGM-HF study in patients with HFrEF, which was stopped early when it was shown Entresto significantly reduced the risk of cardiovascular death versus ACE-inhibitor enalapril
TM)](sacubitril/valsartan) tablets were readmitted to the hospital for heart failure or for any cause within 30 days of discharge from a heart failure hospitalization compared to patients treated with enalapril
In a study that included more than 20,000 adults in China with high blood pressure, but without a history of stroke or heart attack, the combined use of the hypertension medication enalapril
and folic acid, compared with enalapril
alone, significantly reduced the risk of first stroke, according to a study published in JAMA.
One medicine often used is an ACE inhibitor, and the study tested one of these -- enalapril
, sold as Vasotec and in generic form -- against the Novartis drug.
Researchers claim the new compound, named LCZ696, can replace enalapril
as the first-choice treatment for heart failure.
This PIP agreement perfectly complements the company's agreement for a PIP on our drug enalapril
earlier this year.
Some commonly used daily drugs are Pantocid for acidity and gastro problems, Enalapril
and Dopamine for blood pressure, Paracetamol for normal viral control to antibiotics like Ronflox and Oflomac.
The purpose of this study was to investigate whether breviscapine combined with enalapril
(an ACE inhibitor) have superior renoprotective effects against diabetic nephropathy.
Study design was similar in five trials, comparison between a placebo arm and a treatment arm with either an ACE inhibitor (perindopril in PEP-CHF and enalapril
study) or ARB (irbesartan in IPRESERVE, candesartan in CHARM Preserved and valsartan in Valsartan study).
is an ACE inhibitor, one of a class of drugs commonly used to control blood pressure and kidney disease.
Two groups were administered one of two antihypertensive medications, losartan or enalapril
, and the last group, a placebo.
As part of the hospital protocol, enalapril
was omitted on the day of the surgery and he had spinal anaesthesia supplemented with general anaesthesia which was uneventful.