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Noun1.encainide - antiarrhythmic drug (trade name Enkaid) used to treat life-threatening arrhythmias but increases the risk of sudden death in heart attack patients
antiarrhythmic, antiarrhythmic drug, antiarrhythmic medication - a drug used to treat an abnormal heart rhythm
References in periodicals archive ?
Mortality and morbidity in patients receiving encainide, flecainide, or placebo--the Cardiac Arrhythmia Suppression Trial.
Norvir should not be taken with the following medicines: astemizole, terfenadine, amiodarone, bepridil, encainide, flecainide, propafenone, quinidine, dihydroergotamine, ergotamine, ergonovine, methylergonovine, clorazepate, diazepam, estazolam, flurazepam, triazolam or oral (taken by mouth) midazolam, clozapine, pimozide, pethidine, piroxicam, propoxyphene, cisapride rifabutin, voriconazole, simvastatin, lovastatin, alfuzosin, fusidic acid, sildenafil used to treat a lung disease called pulmonary arterial hypertension, and products containing St John's wort (Hypericum perforatum).
encainide or flecainide) or peripheral vasodilators without re-titration has resulted in lethal pro-arrhythmia or hypotension, respectively.
The drugs used were encainide, flecainide and moricizine.
One frequently cited case involves the anti-arrhythmia drugs encainide and flecainide.
In the US, dogs failed to predict heart problems caused by the cardiovascular drugs encainide and flecainide which led to an estimated 3,000 deaths.
Researchers suggested the interaction between ischemia and treatment with encainide or flecainide may have been responsible for the increased mortality seen in the treatment group.