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Related to endolymphatic: endolymphatic duct, endolymphatic sac


The fluid in the membranous labyrinth of the inner ear.

en′do·lym·phat′ic (-lĭm-făt′ĭk) adj.
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Internal and external openings of the endolymphatic duct are also preserved (Fig.
The main types of vestibular injuries associated with TBI are benign paroxysmal positional vertigo (BPPV) (the most common peripheral vestibular disorder), labyrinthine injury and traumatic endolymphatic hydrops.
This may occur either when the deposits abnormally attach to the cupula (cupulolithiasis) or when the dense particles freely move in the endolymphatic fluid in the semicircular canals (canalolithiasis) (2).
It may present with hemangioblastomas in the brain, spinal cord, and retina; renal cysts and clear cell renal cell carcinoma; pheochromocytoma; pancreatic cysts and neuroendocrine tumors; endolymphatic sac tumors; and epididymal and ligamentum latum cysts.
GJB2 encodes the gap junction protein Connexin 26 (CX26), which is expressed in the cochlea and plays an important role in endolymphatic potassium recycling.
sup][24] The degree of endolymphatic hydrops in Meniere's disease has its regulated changes during progression.
4) Genetic predisposition to the development of CCRCC (termed VHL syndrome) is associated with germline VHL mutations, and patients with the VHL gene often develop numerous, bilateral CCRCCs beginning at an early age (5); they may also develop paragangliomas, pancreatic tumors, hemangioblastomas, endolymphatic sac tumors, and papillary cystadenomas of the epididymis/ broad ligament.
Extracellular adenosine 5'-triphosphate (ATP) in the endolymphatic compartment influences cochlear function.
About 20% are associated with Hippel-Lindau disease in which multiple lesions are seen with endolymphatic sac tumour.
Endolymphatic sac tumours (ELST) occur in 11-16% of VHL patients.
The endolymphatic sac is believed to regulate endolymphatic pressure, fluid volume, and ionic balance within the inner ear.