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endostatin

   Also found in: Medical, Wikipedia 0.03 sec.
en·do·stat·in  (nd-sttn)
n.
A potent, naturally occurring antiangiogenic protein that inhibits the formation of the blood vessels that feed tumors. It is under investigation as a potential cancer therapy.



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For example, Judah Folkman first envisioned the idea of angiogenesis at the beginning of his career, more than forty years ago, yet neither endostatin nor angiostatin, the potent antiangiogenesis drugs he developed, nor others in this category that have been developed by other researchers, had been approved by the Food and Drug Administration in mid-2004.
Anderson Cancer Center labeled the experimental drug endostatin with a radioactive tag.
Also featured are patients participating in endostatin trials and other therapies pioneered by Folkman, who is director of Surgical Research Libraries at Children's Hospital in Boston and professor of surgery and cell biology at Harvard Medical School.
 
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