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Related to enfuvirtide: Maraviroc


An antiretroviral drug of the fusion inhibitor class used in combination with other drugs to treat HIV infection.

[en(try/)fu(sion inhibitor) + -vir, antiviral suff. (ultimately from virus) + (pep)tide.]


n enfuvirtida
References in periodicals archive ?
Part 4 - Description: enfuvirtide | 108mg | vial | 60 - the number of packs: 10 packs
FDA-Approved Antiretroviral Agents Nucleoside RTIs Nonnucleoside RTIs Protease inhibitors abacavir (ABC) delavirdine (DLV) atazanavir (ATV) didanosine (ddl) efavirenz (EFZ) darunavir (DRV) emtricitabine (FTC) etravirine (ETV) fosamprenavir (Fos-APV) lamivudine (3TC) nevirapine (NVP) indinavir (IDV) stavudine (d4T) lopinavir/r (LPV/r) zidovudine (ZDV) nelfinavir (NFV) ritonavir (RTV) saquinavir (SQV) tipranavir (TPV) Nucleotide RTI Integrase inhibitor Fusion inhibitor tenofovir DF (TDF) raltegravir (RAL) enfuvirtide (T-20) CCR5 antagonist maraviroc (MVC) Notes: Six fixed-dose combinations are approved by the Food and Drug Administration.
We maintain them on protease inhibitors because of some possible CD4 benefit, and we consider maintaining them on an integrase inhibitor or enfuvirtide or maraviroc for some immunologic benefit.
However, the fusion inhibitor, enfuvirtide, has so far shown little liver toxicity [51].
Unlike other HIV agents, enfuvirtide (Fuzeon) is a fusion inhibitor that binds to the gp41 protein of the virus and prevents the virus from infecting healthy cells.
Most antiretroviral agents are only available as oral tablets and suspensions, except zidovudine and enfuvirtide, which are available in parenteral form.
Fuzeon for Injection" is a white to off-white, sterile, lyophilized (freeze-dried) powder and it is packaged in a single-use clear glass vial containing 108 milligrams of enfuvirtide for the delivery of approximately 90 milligrams per milliliter when reconstituted with 1.
Patients' background regimens were based on the results of resistance testing and included a fully-active ritonavir-boosted protease inhibitor, and a second agent that was permitted to be a nucleoside or nucleotide reverse transcriptase inhibitor, etravirine, maraviroc or enfuvirtide.
600Mg 90000 18000011 Emtricitab Inum Caps 200Mg 6000 1200012 Units Enfuvirtide Powder.
Combination of raltegravir, enfuvirtide, and darunavir 126
Most currently approved antiretroviral drugs, with the exception of enfuvirtide and maraviroc, target the HIV viral enzymes.
The response rate was even more impressive in the subgroup whose background medications included enfuvirtide, also known as T20, an anti-HIV entry inhibitor.