M2 PHARMA-February 2, 2018-DNA Script Partners with DCC to Enable Enzymatically
synthesized lactose monodecanoate (LMD) and lactose monolaurate (LML) exhibit greater microbial inhibitory properties against Gram-positive bacteria than lactose monomyristate (LMM) and lactose monooctanoate (LMO).
They are naturally occurring carbohydrates that WACKER produces enzymatically
from plant-based raw materials such as corn or potatoes.
After MORAb-202 enters the target cancer cells, the linker is enzymatically
cleaved, separating eribulin, the payload, from the antibody.
Scientists have uncovered an enzymatically
modified rice bran that has been shown to increase NK-cell activity by up to 84%.
measured creatinine concentration (Roche Diagnostics, COBAS 8000) was significantly decreased 24 h after admission (Table 1), inconsistent with clinical features and blood urea nitrogen concentration.
These linkers include: hydrazones--releasing the drug in acidic conditions within lysozomes of the target cells; peptides--hydrolyzed enzymatically
by lysosomal proteases; and disulfides--undergo intracellular reduction reactions.
Xiapex is a combination of two purified clostridial collagenases for injection that enzymatically
disrupts the contracting cord and collagen plaque and reduces the contraction.
There is very limited information regarding the effects of enzymatically
hydrolyzed yeast (EHY) cell wall components on growth performance of feedlot cattle, particularly during period of high ambient temperature to which a majority of feedlot cattle will be exposed during some portion of the growing-finishing period.
Due to its moderate hydrophobicity, APPS penetrates effectively into the dermis, the third skin layer, where it is then enzymatically
converted to ascorbic acid (vitamin C).
Acetobacter and Gluconobacter can oxidize ethanol to acetic acid enzymatically
with alcohol dehydrogenase (first oxidized to acetaldehyde then to acetate with aldehyde dehydrogenase).
According to the company, Xiapex (collagenase clostridium histolyticum) is a combination of two purified clostridial collagenases for injection that enzymatically
disrupts the contracting cord and reduces the contraction.